Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Jan 31:11:5.
doi: 10.4103/abr.abr_91_21. eCollection 2022.

Schwannoma of the Rectosigmoid Colon

Maral Mokhtari  1 , Pooya Iranpour  2 , Ardalan Golbahar Haghighi  3 , Leila Ghahramani  4
Affiliations
Case Reports

Schwannoma of the Rectosigmoid Colon

Maral Mokhtari et al. Adv Biomed Res. .

Abstract

Schwannoma is a rare tumor in the colon which originates from the peripheral nerve plexus. Most of the cases have been asymptomatic but occasionally present as an obstructive mass. Abdominal investigations are effective in some cases, but usually, they are not informative. A significant number of cases have been detected after their operation by histopathology examination. Immune and histochemical staining shows the spindle cells that have been positive for S-100 and vimentin, but negative for CD34 and smooth muscle actin. If the diagnosis of Schowannoma is confirmed preoperatively, segmental resection is recommended. In this case report, we presented a 58-year-old woman with pelvic mass and normal colonoscopy that mimic extramural large uterine myoma with extraluminal pressure effect on the rectosigmoid.

Keywords: Colon; colonoscopy; rectum; schwannoma; sigmoid; surgery; tumor.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Axial contrast-enhanced abdominal computed tomography scan through the pelvic cavity demonstrates a 67 mm × 51 mm almost homogeneous enhancing mass (asterisk) arising from the wall of the proximal part of the rectum. Several enlarged lymph nodes are also detectable (black arrows)
Figure 2
Figure 2
Axial section through the more superior part reveals the mass arising from the rectal wall (white arrow)
Figure 3
Figure 3
Histopathological examination of the mass shows hypo-and hyper-cellular areas with thick wall hyalinized blood vessels, H and E, ×200
Figure 4
Figure 4
Strong and diffuse S100 immunostaining
Figure 5
Figure 5
Ki-67 immunolabeling showed 3%–4% proliferation index
Figure 6
Figure 6
Immunostaining of CD34 which is negative in the tumor cells in contrast to staining of the vessels
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Trivedi A, Ligato S. Microcystic/reticular schwannoma of the proximal sigmoid colon: Case report with review of literature. Arch Pathol Lab Med. 2013;137:284–8. - PubMed
    1. Çakır T, Aslaner A, Yaz M, rıza Gündüz U. Schwannoma of the sigmoid colon. Case Reports. 2015;2015:bcr2014208934. - PMC - PubMed
    1. Bohlok A, El Khoury M, Bormans A, Galdon MG, Vouche M, El Nakadi I, et al. Schwannoma of the colon and rectum: A systematic literature review. World J Surg Oncol. 2018;16:125. - PMC - PubMed
    1. Yoon HY, Kim CB, Lee YH, Kim HG. Gastric schwannoma. Yonsei Med J. 2008;49:1052–4. - PMC - PubMed
    1. Shu Z, Li C, Sun M, Li Z. Intestinal schwannoma: A clinicopathological, immunohistochemical, and prognostic study of 9 cases. Gastroenterol Res Pract. 2019;2019:3414678. - PMC - PubMed

Publication types