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Review
. 2023 Mar;62(3):404-415.
doi: 10.1111/ijd.16109. Epub 2022 Feb 26.

A systematic review on the lipid composition of human hair

David A Csuka  1 , Ella A Csuka  1 , Margit L W Juhász  1 , Ajay N Sharma  1 , Natasha A Mesinkovska  1
Affiliations
Review

A systematic review on the lipid composition of human hair

David A Csuka et al. Int J Dermatol. 2023 Mar.

Abstract

Hair lipid composition varies by ethnic hair type and by hair layer. Lipids in the cuticle, cortex, and medulla of the hair shaft provide a protective barrier to environmental and chemical damage, prevent hair breakage and desorption, and affect the elastic and tensile properties of hair. The aim of this systematic review is to provide an overview of the lipid composition and ethnic differences of human hair, effects of external damage on lipid content and properties, and changes in hair lipid composition associated with disease states. PubMed/MEDLINE was searched up to March 2021 according to PRISMA guidelines for articles discussing the lipid content of human hair and effects of physical, chemical, or environmental damage, and disease. Fifty-nine articles investigating the lipid content of hair were included for review. Lipids affect fluid permeability, hydration, strength, and texture of ethnic hair fibers. Lipid loss is accelerated by hair-damaging treatments such as bleach, dye, perm, straightening, and surfactant use, and sun and aging processes, leading to dehydrated, breakable, disordered, and dull hair. Diseases including acne, alopecia, and breast, gastric, prostate, lung, and rectal cancers display elevated hair lipid levels. Lipids are vital in protection against damage and maintenance of healthy hair. Further studies are needed to investigate the effects of lipids on the structural properties of ethnic hair, and changes in hair lipid composition with various dermatologic and systemic diseases.

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References

    1. Lee WS, Oh TH, Chun SH, et al. Integral lipid in human hair follicle. J Investig Dermatol Symp Proc 2005; 10: 234-237.
    1. Coderch L, Oliver MA, Martínez V, et al. Exogenous and endogenous lipids of human hair. Skin Res Technol 2017; 23: 479-485. https://doi.org/10.1111/srt.12359
    1. Dawber R. Hair: its structure and response to cosmetic preparations. Clin Dermatol 1996; 14: 105-112. https://doi.org/10.1016/0738-081X(95)00117-X
    1. Robbins CR. Chemical and Physical Behavior of Human Hair. Berlin: Springer, 2012. https://doi.org/10.1007/978-3-642-25611-0
    1. Okamotoy M, Ishikawa K, Tanji N, et al. Structural analysis of the outermost hair surface using TOF-SIMS with C60 depth profiling technique. E-Journal of Surface Science and Nanotechnology 2012; 10: 234-238. https://doi.org/10.1380/ejssnt.2012.234

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