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. 2023 Jan;315(1):67-73.
doi: 10.1007/s00403-021-02306-y. Epub 2022 Feb 2.

Factors affecting outcomes of second intent healing of nasal defects after Mohs micrographic surgery

David Nam-Woo Kim  1 , Nour Kibbi  2 , Sean R Christensen  3 , David J Leffell  3 , Kathleen C Suozzi  4   5
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Factors affecting outcomes of second intent healing of nasal defects after Mohs micrographic surgery

David Nam-Woo Kim et al. Arch Dermatol Res. 2023 Jan.

Abstract

Reconstruction of nasal defects secondary to Mohs micrographic surgery (MMS) presents particular challenges related to the complex topography, skin quality, tissue laxity, and functional and aesthetic concerns of the region. Factors affecting outcomes resulting from second intent healing (SIH) on the nose have not been well described. The purpose of the study was to identify factors impacting outcomes of SIH for nasal tumors following MMS. Retrospective analysis was performed of all nasal lesions treated with MMS followed by SIH from a single surgical center over a 1.5-year period. Ninety-six cases were included. Chart review was performed, and data were collected including age, gender, nasal site, tumor type, defect size, depth, and number of MMS stages. Pre- and post-operative follow-up photographs were available for all cases. All five authors evaluated the photographs using the modified Manchester scar scale. Analysis was then conducted to identify features associated with good outcomes. Of the 96 tumors, 39 lesions (40.6%) were located on the nasal tip (including supratip), 32 (33.3%) on the ala/alar groove, 17 (17.7%) on the sidewall, and 8 (8.3%) on the dorsum. The average defect size was 0.83 cm2 (diameter of 1.06 cm ± 0.4). Defect diameter and defect depth were the factors that significantly impacted scar outcome (p < 0.001) in multivariate analysis. No significant functional deficits were reported. This retrospective study suggests that nasal defects with area less than 0.83 cm2 (or 1.06 cm diameter) and depth of defect not extending beyond the superficial fat healed well by SIH regardless of location on the nose.

Keywords: Basal cell carcinoma; Mohs micrographic surgery; Non-melanoma skin cancer; Second intention healing; Squamous cell carcinoma; Wound healing.

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