Idiopathic hypersomnia: does first to approval mean first-line treatment?
- PMID: 34942131
- PMCID: PMC9089235
- DOI: 10.1016/S1474-4422(21)00419-1
Idiopathic hypersomnia: does first to approval mean first-line treatment?
Conflict of interest statement
LMT is a member of the Board of Directors of the American Academy of Sleep Medicine (AASM). All opinions expressed are those of LMT and do not necessarily reflect those of the AASM.
Comment on
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Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study.Lancet Neurol. 2022 Jan;21(1):53-65. doi: 10.1016/S1474-4422(21)00368-9. Lancet Neurol. 2022. PMID: 34942138
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References
-
- FDA Grants First of its Kind Indication for Chronic Sleep Disorder Treatment. published 8/12/21. https://www.fda.gov/news-events/press-announcements/fda-grants-first-its... (accessed 11/3/21.
-
- Dauvilliers Y, Arnulf I, Foldvary-Schaefer N, et al. Efficacy and Safety of Lower-Sodium Oxybate in Adults With Idiopathic Hypersomnia: A Phase 3, Placebo-Controlled, Double-Blind, Randomized Withdrawal Study. Lancet Neurol 2022. - PubMed
-
- Mayer G, Benes H, Young P, Bitterlich M, Rodenbeck A. Modafinil in the treatment of idiopathic hypersomnia without long sleep time-a randomized, double-blind, placebo-controlled study. J Sleep Res 2015; 24(1): 74–81. - PubMed
-
- Inoue Y, Tabata T, Tsukimori N. Efficacy and safety of modafinil in patients with idiopathic hypersomnia without long sleep time: a multicenter, randomized, double-blind, placebo-controlled, parallel-group comparison study. Sleep Med 2021; 80: 315–21. - PubMed
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