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Comment
. 2021 Oct;27(10):1689-1690.
doi: 10.1038/s41591-021-01525-0. Epub 2021 Oct 11.

Challenges with benchmarking of MDMA-assisted psychotherapy

Joar Øveraas Halvorsen  1   2 , Florian Naudet  3 , Ioana A Cristea  4
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Comment

Challenges with benchmarking of MDMA-assisted psychotherapy

Joar Øveraas Halvorsen et al. Nat Med. 2021 Oct.
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  • MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study.
    Mitchell JM, Bogenschutz M, Lilienstein A, Harrison C, Kleiman S, Parker-Guilbert K, Ot'alora G M, Garas W, Paleos C, Gorman I, Nicholas C, Mithoefer M, Carlin S, Poulter B, Mithoefer A, Quevedo S, Wells G, Klaire SS, van der Kolk B, Tzarfaty K, Amiaz R, Worthy R, Shannon S, Woolley JD, Marta C, Gelfand Y, Hapke E, Amar S, Wallach Y, Brown R, Hamilton S, Wang JB, Coker A, Matthews R, de Boer A, Yazar-Klosinski B, Emerson A, Doblin R. Mitchell JM, et al. Nat Med. 2021 Jun;27(6):1025-1033. doi: 10.1038/s41591-021-01336-3. Epub 2021 May 10. Nat Med. 2021. PMID: 33972795 Free PMC article. Clinical Trial.

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References

    1. Mitchell, J. M. et al. MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study. Nat. Med. https://doi.org/10.1038/s41591-021-01336-3 (2021).
    1. American Psychological Association. Clinical practice Guideline for the Treatment of Posttraumatic Stress Disorder (PTSD) in Adults 1st edn (APA, 2017).
    1. National Institute for Health and Care Excellence. Post-traumatic Stress Disorder. NIC Guideline [NG116] (National Institute for Health and Care Excellence, 2018).
    1. Lee, D. J. et al. Psychotherapy versus pharmacotherapy for posttraumatic stress disorder: Systemic review and meta- analyses to determine first-line treatments. Depress. Anxiety 33, 792–806 (2016). - DOI
    1. Mavranezouli, I. et al. Psychological treatments for post-traumatic stress disorder in adults: a network meta-analysis. Psychol. Med. 50, 542–555 (2020). 130. - DOI

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