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. 2021 Oct 1;34(4):417-426.
doi: 10.3344/kjp.2021.34.4.417.

Determinants of depression in non-cardiac chest pain patients: a cross sectional study

Hamidreza Roohafza  1 , Niloufar Yavari  2 , Awat Feizi  3 , Azam Khani  4 , Parsa Saneian  2 , Sara Bagherieh  2 , Fereshteh Sattar  4 , Masoumeh Sadeghi  1
Affiliations

Determinants of depression in non-cardiac chest pain patients: a cross sectional study

Hamidreza Roohafza et al. Korean J Pain. .

Abstract

Background: Non-cardiac chest pain (NCCP) is a common patient complaint imposing great costs on the healthcare system. It is associated with psychological factors such as depression. The aim of the present study is determining depression predictors in NCCP patients.

Methods: The participants of this cross-sectional study were 361 NCCP patients. Patients filled out questionnaires concerning their sociodemographic, lifestyle, and clinical factors (severity of pain, type D personality, somatization, cardiac anxiety, fear of body sensations, and depression).

Results: Based on multiple ordinal logistic regression, lack of physical activity (odds ratio [OR], 1.78; 95% confidence interval [CI], 1.09-2.87), sleep quality (OR, 2.98; 95% CI, 1.15-7.69), being a smoker (OR, 1.33; 95% CI, 2.41-4.03), present pain intensity (OR, 1.08; 95% CI, 1.05-1.11), type D personality (OR, 2.43; 95% CI, 1.47- 4.03), and somatization (OR, 1.22; 95% CI, 1.15-1.3) were significant predictors of depression in NCCP patients. Additionally, multiple linear regression showed that being unmarried (β = 1.51, P = 0.008), lack of physical activity (β = 1.22, P = 0.015), sleep quality (β = 2.26, P = 0.022), present pain intensity (β = 0.07, P = 0.045), type D personality (β = 1.87, P < 0.001), somatization (β = 0.45, P < 0.001), and fear of bodily sensation (β = 0.04, P = 0.032) increased significantly depression scores in NCCP patients.

Conclusions: Physicians should consider the predictors of depression in NCCP patients which can lead to receiving effective psychological consultations and reducing the costs and ineffectual referrals to medical centers.

Keywords: Anxiety; Chest Pain; Cross-Sectional Studies; Depression; Life Style; Psychology; Somatoform Disorders; Type D Personality..

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Conflict of interest statement

CONFLICT OF INTEREST

No potential conflict of interest relevant to this article was reported.

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References

    1. Meresh E, Piletz J, Halaris A. Noncardiac chest pain: systematic review of the literature on prognosis. Res Rep Clin Cardiol. 2018;9:1–9. doi: 10.2147/RRCC.S155441. https://doi.org/10.2147/RRCC.S155441 . - DOI
    1. Schroeder S, Achenbach S, Körber S, Nowy K, de Zwaan M, Martin A. Cognitive-perceptual factors in noncardiac chest pain and cardiac chest pain. Psychosom Med. 2012;74:861–8. doi: 10.1097/PSY.0b013e31826ae4ae. - DOI - PubMed
    1. Mourad G, Alwin J, Strömberg A, Jaarsma T. Societal costs of non-cardiac chest pain compared with ischemic heart disease--a longitudinal study. BMC Health Serv Res. 2013;13:403. doi: 10.1186/1472-6963-13-403. - DOI - PMC - PubMed
    1. Castonguay J, Turcotte S, Fleet RP, Archambault PM, Dionne CE, Denis I, et al. Physical activity and disability in patients with noncardiac chest pain: a longitudinal cohort study. Biopsychosoc Med. 2020;14:12. doi: 10.1186/s13030-020-00185-9. - DOI - PMC - PubMed
    1. Mourad G, Alwin J, Jaarsma T, Strömberg A, Johansson P. The associations between psychological distress and health-related quality of life in patients with non-cardiac chest pain. Health Qual Life Outcomes. 2020;18:68. doi: 10.1186/s12955-020-01297-0. - DOI - PMC - PubMed

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