Meta-Analysis

. 2021 Mar;52(1):80-84.

doi: 10.1007/s12029-020-00529-2. Epub 2020 Oct 1.

Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk

Mohammad Hossein Jarahzadeh¹, Fatemeh Asadian², Meraj Farbod³, Bahare Meibodi⁴, Hajar Abbasi⁵, Mohammadali Jafari⁶, Ali Raee-Ezzabadi⁶, Reza Bahrami⁷, Hossein Neamatzadeh^{8

9}

Affiliations

¹ Department of Anesthesiology and Critical Care, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
² Department of Medical Laboratory Sciences, School of Paramedical Science, Shiraz University of Medical Sciences, Shiraz, Iran. asadian@sums.ac.ir.
³ Cancer Institute, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
⁴ Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁵ Department of Obstetrics and Gynecology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁶ Department of Emergency Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁷ Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
⁸ Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁹ Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

PMID: 33001376
PMCID: PMC7527425
DOI: 10.1007/s12029-020-00529-2

Meta-Analysis

Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk

Mohammad Hossein Jarahzadeh et al. J Gastrointest Cancer. 2021 Mar.

. 2021 Mar;52(1):80-84.

doi: 10.1007/s12029-020-00529-2. Epub 2020 Oct 1.

Authors

Mohammad Hossein Jarahzadeh¹, Fatemeh Asadian², Meraj Farbod³, Bahare Meibodi⁴, Hajar Abbasi⁵, Mohammadali Jafari⁶, Ali Raee-Ezzabadi⁶, Reza Bahrami⁷, Hossein Neamatzadeh^{8

9}

Affiliations

¹ Department of Anesthesiology and Critical Care, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
² Department of Medical Laboratory Sciences, School of Paramedical Science, Shiraz University of Medical Sciences, Shiraz, Iran. asadian@sums.ac.ir.
³ Cancer Institute, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
⁴ Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁵ Department of Obstetrics and Gynecology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁶ Department of Emergency Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁷ Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
⁸ Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
⁹ Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

PMID: 33001376
PMCID: PMC7527425
DOI: 10.1007/s12029-020-00529-2

Abstract

Background: The presence of comorbidity poses a major clinical challenge in the care and treatment of COVID-19 patients. Moreover, having one or more comorbidities could be a life-threatening situation in COVID-19 patients. Cancer is substantially associated with significant morbidity and mortality in COVID-19 patients. However, there is not sufficient data to conclude that cancer patients have a higher risk of COVID-19 infection. In this study, we reviewed cancer comorbidity and risk of mechanical ventilation or death in patients with confirmed COVID-19.

Methods: A comprehensive systematic search was performed on PubMed, Scopus, Web of Science, SciELO, and CNKI, to find articles published until August 01, 2020. All relevant case series, case reports, systematic and narrative reviews, meta-analyses, and prospective and retrospective studies that reported clinical characteristics and epidemiological information of cancer patients infected with COVID-19 were included in the study.

Results: A total of 12 cohort studies exclusively on cancer patients with confirmed COVID-19 were selected.

Conclusions: According to the findings of this study, cancer was not among the most prevalent underlying diseases in patients with confirmed COVID-19. Moreover, cancer patients infected with COVID-19 had the lowest risk of mechanical ventilation or death than the non-cancer infected patients.

Keywords: COVID-19; Cancer; Death; Intensive care unit; Malignancy; Ventilation.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

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Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk

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Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk

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