(Hybrid) SPECT and PET Technologies
- PMID: 32594385
- DOI: 10.1007/978-3-030-42618-7_3
(Hybrid) SPECT and PET Technologies
Abstract
SPECT and PET are nuclear tomographic imaging modalities that visualize functional information based on the accumulation of radioactive tracer molecules. However, SPECT and PET lack anatomical information, which has motivated their combination with an anatomical imaging modality such as CT or MRI. This chapter begins with an overview over the fundamental physics of SPECT and PET followed by a presentation of the respective detector technologies, including detection requirements, principles and different detector concepts. The reader is subsequently provided with an introduction into hybrid imaging concepts, before a dedicated section presents the challenges that arise when hybridizing SPECT or PET with MRI, namely, mutual distortions of the different electromagnetic fields in MRI on the nuclear imaging system and vice versa. The chapter closes with an overview about current hybrid imaging systems of both clinical and preclinical kind. Finally, future developments in hybrid SPECT and PET technology are discussed.
Similar articles
-
SPECT/CT, PET/CT and PET/MRI: oncologic and infectious applications and protocol considerations.Pediatr Radiol. 2023 Jun;53(7):1443-1453. doi: 10.1007/s00247-023-05597-7. Epub 2023 Mar 11. Pediatr Radiol. 2023. PMID: 36899268 Review.
-
[Hybrid imaging: clinical evidence, opportunities].Orv Hetil. 2015 Dec 27;156(52):2110-5. doi: 10.1556/650.2015.30324. Orv Hetil. 2015. PMID: 26686747 Review. Hungarian.
-
Hybrid Imaging in Oncology.Asian Pac J Cancer Prev. 2015;16(14):5599-605. doi: 10.7314/apjcp.2015.16.14.5599. Asian Pac J Cancer Prev. 2015. PMID: 26320423 Review.
-
Recent advances in hybrid molecular imaging systems.Semin Musculoskelet Radiol. 2014 Apr;18(2):103-22. doi: 10.1055/s-0034-1371014. Epub 2014 Apr 8. Semin Musculoskelet Radiol. 2014. PMID: 24715444 Review.
-
Hybrid imaging by SPECT/CT and PET/CT: proven outcomes in cancer imaging.Semin Nucl Med. 2009 Jul;39(4):276-89. doi: 10.1053/j.semnuclmed.2009.03.003. Semin Nucl Med. 2009. PMID: 19497404 Review.
Cited by
-
RNA nanostructures for targeted drug delivery and imaging.RNA Biol. 2024 Jan;21(1):1-19. doi: 10.1080/15476286.2024.2328440. Epub 2024 Mar 31. RNA Biol. 2024. PMID: 38555519 Free PMC article. Review.
-
Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging.Nanomaterials (Basel). 2023 Mar 19;13(6):1102. doi: 10.3390/nano13061102. Nanomaterials (Basel). 2023. PMID: 36985996 Free PMC article. Review.
-
Radiolabeled nanomaterial for cancer diagnostics and therapeutics: principles and concepts.Cancer Nanotechnol. 2023;14(1):15. doi: 10.1186/s12645-023-00165-y. Epub 2023 Feb 27. Cancer Nanotechnol. 2023. PMID: 36865684 Free PMC article. Review.
-
Spectral Photon-Counting CT Imaging of Gold Nanoparticle Labelled Monocytes for Detection of Atherosclerosis: A Preclinical Study.Diagnostics (Basel). 2023 Jan 29;13(3):499. doi: 10.3390/diagnostics13030499. Diagnostics (Basel). 2023. PMID: 36766602 Free PMC article.
-
Imaging of Uveal Melanoma-Current Standard and Methods in Development.Cancers (Basel). 2022 Jun 27;14(13):3147. doi: 10.3390/cancers14133147. Cancers (Basel). 2022. PMID: 35804919 Free PMC article. Review.