Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jan:65:54-61.
doi: 10.1016/j.sleep.2019.07.008. Epub 2019 Jul 22.

Associations of sleep duration, sedentary behaviours and energy expenditure with maternal glycemia in pregnancy

Myriam Doyon  1 , Laura Pelland-St-Pierre  2 , Catherine Allard  1 , Luigi Bouchard  3 , Patrice Perron  4 , Marie-France Hivert  5
Affiliations

Associations of sleep duration, sedentary behaviours and energy expenditure with maternal glycemia in pregnancy

Myriam Doyon et al. Sleep Med. 2020 Jan.

Abstract

Background: Women with high levels of physical activity (PA) are less likely to develop gestational diabetes mellitus (GDM), but the relations with sleep and sedentary behaviours (SB) are more controversial. We aimed to investigate all three components (sleep, PA, and SB) and their association with maternal glucose in pregnancy.

Methods: We included 766 pregnant women recruited at first trimester and that we followed at second trimester. We collected blood samples, anthropometry and standardized questionnaires about lifestyle including PA, SB, and sleep duration at both visits. Women completed a 50 g glucose challenge test at first trimester and 75-g oral glucose tolerance test (OGTT) at second trimester. We conducted regression analyses to test cross-sectional associations between sleep, PA, and SB with maternal glucose levels while taking into account potential confounders (maternal age, pre-pregnancy body mass index (BMI), gravidity, and smoking). We considered linear and quadratic relationships.

Results: At first trimester, we observed a linear relationship between shorter sleep duration and higher glucose levels, which was attenuated after adjustments for confounders. At second trimester, we found a quadratic relationship between sleep and glucose showing lowest levels at fasting and 1 h-post OGTT for women who slept 6-10 h/night. This association remained significant after adjusting for confounders and taking into account PA and/or SB. Greater amount of SB was associated with higher 1 h-glucose after adjustment for confounders (β = 0.132; SE = 0.047; P = 0.005).

Conclusions: Sleep duration is associated with glucose regulation in pregnancy, independently of PA and SB, and this association varies according to the period of gestation.

Keywords: Glycemic regulation; Leisure physical activity; Pregnancy; Sedentary behavior; Sleep duration.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

Publication types