Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Anoxic Encephalopathy

Zachary Messina  1 , Angela Hays Shapshak  2 , Rebecca Mills  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
.
Affiliations
Free Books & Documents
Book

Anoxic Encephalopathy

Zachary Messina et al.
Free Books & Documents

Excerpt

Anoxic encephalopathy, or hypoxic-ischemic brain injury, is a process that begins with the cessation of cerebral blood flow to brain tissue, which most commonly results from poisoning (for example, carbon monoxide or drug overdose), vascular injury or insult, or cardiac arrest. Many patients who suffer anoxic brain injury expire without regaining full consciousness, and many patients have significantly poor neurologic outcomes. However, some advances are beginning to demonstrate the preservation of brain tissue, and there is a focus on identifying patients with the prospect of improving neurologic morbidity and mortality.

There has been published data to indicate that there are predictors for poor outcomes. However, evidence of factors suggestive of good prognosis or outcome has lagged. This activity will review the literature and practices concerning anoxic encephalopathy and brain injury.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Zachary Messina declares no relevant financial relationships with ineligible companies.

Disclosure: Angela Hays Shapshak declares no relevant financial relationships with ineligible companies.

Disclosure: Rebecca Mills declares no relevant financial relationships with ineligible companies.

Similar articles

See all similar articles

References

    1. Hypothermia after Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002 Feb 21;346(8):549-56. - PubMed
    1. Zeiner A, Holzer M, Sterz F, Schörkhuber W, Eisenburger P, Havel C, Kliegel A, Laggner AN. Hyperthermia after cardiac arrest is associated with an unfavorable neurologic outcome. Arch Intern Med. 2001 Sep 10;161(16):2007-12. - PubMed
    1. Allen KA, Brandon DH. Hypoxic Ischemic Encephalopathy: Pathophysiology and Experimental Treatments. Newborn Infant Nurs Rev. 2011 Sep 01;11(3):125-133. - PMC - PubMed
    1. Rajamani A, Seppelt I, Bourne J. Difficulties with neurological prognostication in a young woman with delayed-onset generalised status myoclonus after cardiac arrest due to acute severe asthma. Indian J Crit Care Med. 2011 Apr;15(2):137-9. - PMC - PubMed
    1. Gupta HV, Caviness JN. Post-hypoxic Myoclonus: Current Concepts, Neurophysiology, and Treatment. Tremor Other Hyperkinet Mov (N Y) 2016;6:409. - PMC - PubMed

Publication types

LinkOut - more resources