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Review
. 2017 Mar 28;2(2):127-152.
doi: 10.3233/BPL-160040.

The Effects of Acute Exercise on Mood, Cognition, Neurophysiology, and Neurochemical Pathways: A Review

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Review

The Effects of Acute Exercise on Mood, Cognition, Neurophysiology, and Neurochemical Pathways: A Review

Julia C Basso et al. Brain Plast. .

Abstract

A significant body of work has investigated the effects of acute exercise, defined as a single bout of physical activity, on mood and cognitive functions in humans. Several excellent recent reviews have summarized these findings; however, the neurobiological basis of these results has received less attention. In this review, we will first briefly summarize the cognitive and behavioral changes that occur with acute exercise in humans. We will then review the results from both human and animal model studies documenting the wide range of neurophysiological and neurochemical alterations that occur after a single bout of exercise. Finally, we will discuss the strengths, weaknesses, and missing elements in the current literature, as well as offer an acute exercise standardization protocol and provide possible goals for future research.

Keywords: Running; affect; electroencephalography; hippocampus; neurochemistry; neurogenesis; neuroimaging; prefrontal cortex.

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Figures

Fig.1
Fig.1
The Time Course of Behavioral, Functional, Physiological, and Neurochemical Effects of Acute Exercise.

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References

    1. Voss MW, et al. Bridging animal and human models of exercise-induced brain plasticity. Trends Cogn Sci. 2013;17(10):525–44. - PMC - PubMed
    1. Kramer AF, Erickson KI, Colcombe SJ. Exercise, cognition, and the aging brain. J Appl Physiol (1985). 2006;101(4):1237–42. - PubMed
    1. Duzel E, van Praag H, Sendtner M. Can physical exercise in old age improve memory and hippocampal function? Brain 2016;139(Pt 3):662–73. - PMC - PubMed
    1. Vivar C, Adult hippocampal neurogenesis, aging and neurodegenerative diseases: Possible strategies to prevent cognitive impairment. Curr Top Med Chem. 2015;15(21):2175–92. - PubMed
    1. Vivar C, Potter MC, van Praag H. All about running: Synaptic plasticity, growth factors and adult hippocampal neurogenesis. Curr Top Behav Neurosci. 2013;15:189–210. - PMC - PubMed

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