Review
doi: 10.1055/s-0038-1627471.
Epub 2018 Mar 16.
Neurofibromatosis and Schwannomatosis
Affiliations
- PMID: 29548054
- DOI: 10.1055/s-0038-1627471
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Review
Neurofibromatosis and Schwannomatosis
Semin Neurol.
2018 Feb.
Abstract
Neurofibromatosis 1, neurofibromatosis 2, and schwannomatosis are a group of related classically inherited but often times sporadic tumor suppressor syndromes. Neuro-oncologists should recognize these syndromes, initiate necessary tests in patients with a clinical suspicion, and support genetic counseling of patients and families. In this review, clinical presentation, diagnostic criteria, day-to-day management including supportive care as well as updates on genetics, and experimental treatment strategies are discussed.
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Conflict of interest statement
None.
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