Slow-wave sleep: From the cell to the clinic
- PMID: 29490885
- DOI: 10.1016/j.smrv.2018.01.008
Slow-wave sleep: From the cell to the clinic
Abstract
In recent decades, increasing evidence has positioned slow-wave sleep (SWS) as a major actor in neurophysiological phenomena such as glucose metabolism, hormone release, immunity and memory. This proposed role for SWS, coupled with observations of impaired SWS in several pathologies as well as in aging, has led some researchers to implement methods that could specifically enhance SWS. This review aims to gather the current knowledge extending from the cell to the clinic, in order to construct an overview of what is currently known about so-called SWS. We slowly expand the view from the molecular processes underlying SWS to the cell unit and assembly to cortical manifestations. We then describe its role in physiology and cognition to finally assess its association with clinical aspects. Finally, we address practical considerations for several techniques that could be used to manipulate SWS, in order to improve our understanding of SWS and possibly help the development of treatments for SWS clinical disorders.
Keywords: Deep sleep; EEG; K-complex; Memory consolidation; NREM; SO; SWA; SWS; Sleep.
Copyright © 2018. Published by Elsevier Ltd.
Similar articles
-
A Critical Time-Window for the Selective Induction of Hippocampal Memory Consolidation by a Brief Episode of Slow-Wave Sleep.Neurosci Bull. 2018 Dec;34(6):1091-1099. doi: 10.1007/s12264-018-0303-x. Epub 2018 Nov 9. Neurosci Bull. 2018. PMID: 30413937 Free PMC article.
-
Can Slow-Wave Sleep Enhancement Improve Memory? A Review of Current Approaches and Cognitive Outcomes.Yale J Biol Med. 2019 Mar 25;92(1):63-80. eCollection 2019 Mar. Yale J Biol Med. 2019. PMID: 30923474 Free PMC article. Review.
-
Comparing targeted memory reactivation during slow wave sleep and sleep stage 2.Sci Rep. 2024 Apr 20;14(1):9057. doi: 10.1038/s41598-024-59696-y. Sci Rep. 2024. PMID: 38643331 Free PMC article.
-
Strengthening sleep-autonomic interaction via acoustic enhancement of slow oscillations.Sleep. 2019 May 1;42(5):zsz036. doi: 10.1093/sleep/zsz036. Sleep. 2019. PMID: 30753650 Free PMC article. Clinical Trial.
-
The role of slow wave sleep in the development of dementia and its potential for preventative interventions.Psychiatry Res Neuroimaging. 2020 Dec 30;306:111178. doi: 10.1016/j.pscychresns.2020.111178. Epub 2020 Sep 4. Psychiatry Res Neuroimaging. 2020. PMID: 32919869 Review.
Cited by
-
Slow-wave sleep dysfunction in mild parkinsonism is associated with excessive beta and reduced delta oscillations in motor cortex.Front Neurosci. 2024 Feb 21;18:1338624. doi: 10.3389/fnins.2024.1338624. eCollection 2024. Front Neurosci. 2024. PMID: 38449736 Free PMC article.
-
Enhanced conductive body heat loss during sleep increases slow-wave sleep and calms the heart.Sci Rep. 2024 Feb 26;14(1):4669. doi: 10.1038/s41598-024-53839-x. Sci Rep. 2024. PMID: 38409133 Free PMC article.
-
Correlation of slow-wave sleep with motor and nonmotor progression in Parkinson's disease.Ann Clin Transl Neurol. 2024 Mar;11(3):554-563. doi: 10.1002/acn3.51975. Epub 2023 Dec 14. Ann Clin Transl Neurol. 2024. PMID: 38093699 Free PMC article.
-
[Application of Polysomnography in Common Neurodegenerative Diseases].Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Sep;54(5):1058-1064. doi: 10.12182/20230960304. Sichuan Da Xue Xue Bao Yi Xue Ban. 2023. PMID: 37866969 Free PMC article. Review. Chinese.
-
Sleep and critical illness: a review.Front Med (Lausanne). 2023 Sep 19;10:1199685. doi: 10.3389/fmed.2023.1199685. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37828946 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
