doi: 10.1039/c7cc08928g.
Epub 2018 Jan 4.
Catalytic aziridination with alcoholic substrates via a chromium tetracarbene catalyst
Affiliations
- PMID: 29299550
- PMCID: PMC6136250
- DOI: 10.1039/c7cc08928g
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Catalytic aziridination with alcoholic substrates via a chromium tetracarbene catalyst
Chem Commun (Camb).
.
Abstract
The first examples of aziridination catalysis with a chromium complex are communicated. This tetracarbene chromium complex provides novel catalytic aziridination reactions with protic substrates such as alcohols or amines on the alkene or organic azide and is the most effective catalyst at low alkene loading for aliphatic alkenes to date.
Figures
Example catalytic aziridination reaction with Cr (1) or Fe (2) catalysts.
Proposed catalytic cycle for 1. Calculated free energies (ΔG) for the species are shown in blue in units of kcal/mol.
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