Hemoglobin A1c and diagnosis of diabetes
- PMID: 29292842
- DOI: 10.1111/1753-0407.12640
Hemoglobin A1c and diagnosis of diabetes
Abstract
The prevalence of diabetes is increasing markedly worldwide, especially in China. Hemoglobin A1c is an indicator of mean blood glucose concentrations and plays an important role in the assessment of glucose control and cardiovascular risk. In 2010, the American Diabetes Association included HbA1c ≥6.5% into the revised criteria for the diagnosis of diabetes. However, the debate as to whether HbA1c should be used to diagnose diabetes is far from being settled and there are still unanswered questions regarding the cut-off value of HbA1c for diabetes diagnosis in different populations and ethnicities. This review briefly introduces the history of HbA1c from discovery to diabetes diagnosis, key steps towards using HbA1c to diagnose diabetes, such as standardization of HbA1c measurements and controversies regarding HbA1c cut-off points, and the performance of HbA1c compared with glucose measurements in the diagnosis of diabetes.
Keywords: HbA1c; diabetes; diagnosis; 糖化血红蛋白; 糖尿病; 诊断.
© 2018 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.
Similar articles
-
Prognosis of Intracerebral Hemorrhage with Newly Diagnosed Diabetes Mellitus According to Hemoglobin A1c Criteria.J Stroke Cerebrovasc Dis. 2018 May;27(5):1127-1133. doi: 10.1016/j.jstrokecerebrovasdis.2017.11.019. Epub 2018 Feb 19. J Stroke Cerebrovasc Dis. 2018. PMID: 29605383
-
Erythrocytosis and Performance of HbA1c in Detecting Diabetes on an Oxygen-Deficient Plateau: A Population-based Study.J Clin Endocrinol Metab. 2020 Apr 1;105(4):dgaa001. doi: 10.1210/clinem/dgaa001. J Clin Endocrinol Metab. 2020. PMID: 31904080
-
HbA1c and the diagnosis of diabetes and prediabetes in a middle-aged and elderly Han population from northwest China (HbA1c).J Diabetes. 2013 Sep;5(3):282-90. doi: 10.1111/1753-0407.12035. Epub 2013 May 28. J Diabetes. 2013. PMID: 23452328
-
Implications of using hemoglobin A1C for diagnosing diabetes mellitus.Am J Med. 2011 May;124(5):395-401. doi: 10.1016/j.amjmed.2010.11.025. Am J Med. 2011. PMID: 21531226 Free PMC article. Review.
-
Correlation between glycated haemoglobin and glucose testing for diabetes mellitus screening.Indian J Med Sci. 2013 Jul-Aug;67(7-8):149-54. Indian J Med Sci. 2013. PMID: 24469558 Review.
Cited by
-
Proactive Identification of Patients with Diabetes at Risk of Uncontrolled Outcomes during a Diabetes Management Program: Conceptualization and Development Study Using Machine Learning.JMIR Form Res. 2024 Apr 26;8:e54373. doi: 10.2196/54373. JMIR Form Res. 2024. PMID: 38669074 Free PMC article.
-
Assessing the temporal within-day glycemic variability during hospitalization in patients with type 2 diabetes patients using continuous glucose monitoring: a retrospective observational study.Diabetol Metab Syndr. 2024 Mar 1;16(1):56. doi: 10.1186/s13098-024-01269-0. Diabetol Metab Syndr. 2024. PMID: 38429847 Free PMC article.
-
Nourishing Yin traditional Chinese medicine: potential role in the prevention and treatment of type 2 diabetes.Am J Transl Res. 2024 Jan 15;16(1):234-254. doi: 10.62347/CVNI4988. eCollection 2024. Am J Transl Res. 2024. PMID: 38322552 Free PMC article. Review.
-
Association of glycemic control with hypertension in patients with diabetes: a population-based longitudinal study.BMC Cardiovasc Disord. 2023 Oct 10;23(1):501. doi: 10.1186/s12872-023-03478-3. BMC Cardiovasc Disord. 2023. PMID: 37817110 Free PMC article.
-
Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion.Diabetes Ther. 2024 Jan;15(1):99-110. doi: 10.1007/s13300-023-01482-6. Epub 2023 Sep 30. Diabetes Ther. 2024. PMID: 37777677 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
