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. 2018 Jun;121(3):548-565.
doi: 10.1177/0033294117727747. Epub 2017 Aug 24.

Multiple Group Confirmatory Factor Analysis of the DASS-21 Depression and Anxiety Scales: How Do They Perform in a Cancer Sample?

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Multiple Group Confirmatory Factor Analysis of the DASS-21 Depression and Anxiety Scales: How Do They Perform in a Cancer Sample?

Rina S Fox et al. Psychol Rep. 2018 Jun.

Abstract

The DASS-21 is a public domain instrument that is commonly used to evaluate depression and anxiety in psychiatric and community populations; however, the factor structure of the measure has not previously been examined in oncologic settings. Given that the psychometric properties of measures of distress may be compromised in the context of symptoms related to cancer and its treatment, the present study evaluated the psychometric properties of the DASS-21 Depression and Anxiety scales in cancer patients ( n = 376) as compared to noncancer control participants ( n = 207). Cancer patients ranged in age from 21 to 84 years (mean = 58.3, standard deviation = 10.4) and noncancer control participants ranged in age from 18 to 81 years (mean = 45.0, standard deviation = 11.7). Multiple group confirmatory factor analysis supported the structural invariance of the DASS-21 Depression and Anxiety scales across groups; the factor variance/covariance invariance model was the best fit to the data. Cronbach's coefficient alpha values demonstrated acceptable internal consistency reliability across the total sample as well as within subgroups of cancer patients and noncancer control participants. Expected relationships of DASS-21 Depression and Anxiety scale scores to measures of suicidal ideation, quality of life, self-rated health, and depressed mood supported construct validity. These results support the psychometric properties of the DASS-21 Depression and Anxiety scales when measuring psychological distress in cancer patients.

Keywords: DASS-21; anxiety; cancer; depression; psychometrics.

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Conflict of interest statement

Declaration of Conflicting Interests

The authors declare that that there is no conflict of interest.

Figures

Figure 1
Figure 1
Factor variance/covariance invariance structural model. All values presented were constrained to equivalence across groups. *p < .05

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References

    1. American Cancer Society. Cancer Treatment and Survivorship Facts & Figures 2014–2015. Atlanta: American Cancer Society; 2014.
    1. American College of Surgeons Commission on Cancer. Cancer Program Standards: Ensuring Patient-Centered Care 2015
    1. Andersen BL, DeRubeis RJ, Berman BS, Gruman J, Champion VL, Massie MJ, … Rowland JH. Screening, assessment, and care of anxiety and depressive symptoms in adults with cancer: An American Society of Clinical Oncology guideline adaptation. Journal of Clinical Oncology. 2014;32:1605–1619. - PMC - PubMed
    1. Antony MM, Bieling PJ, Cox BJ, Enns MW, Swinson RP. Psychometric properties of the 42-item and 21-item versions of the Depression Anxiety Stress Scales in clinical groups and a community sample. Psychological Assessment. 1998;10:176–181.
    1. Antony MM, Orsillo SM, Roemer L. Practitioner’s Guide to Empirically Based Measures of Anxiety. New York: Kluwer Academic/Plenum; 2001.