Review
doi: 10.1146/annurev-med-041316-090545.
Epub 2017 Aug 16.
Understanding Peripartum Cardiomyopathy
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- PMID: 28813232
- DOI: 10.1146/annurev-med-041316-090545
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Review
Understanding Peripartum Cardiomyopathy
Annu Rev Med.
.
Abstract
Peripartum cardiomyopathy (PPCM) is the unexplained loss of maternal cardiac systolic function in the period surrounding parturition. PPCM affects women worldwide and is a leading cause of maternal mortality. The cause of PPCM has remained elusive until recently. We review here the epidemiology of PPCM, recent findings that strongly indicate hormonal and genetic contributions to the development of PPCM, and implications for the management of women with PPCM.
Keywords: African-American; peripartum cardiomyopathy; preeclampsia; prolactin; sFlt1.
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