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Review
. 2017 Aug;28(5):426-436.
doi: 10.1097/MCA.0000000000000490.

Coronary intervention for chronic total occlusion: current indications and future directions

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Review

Coronary intervention for chronic total occlusion: current indications and future directions

Janarthanan Sathananthan et al. Coron Artery Dis. 2017 Aug.

Abstract

Chronic total occlusions (CTOs) are routinely encountered during coronary angiography, but subsequent revascularization rates are low. This has likely been driven by a historical belief that there is minimal clinical benefit and poor success rates with a percutaneous coronary intervention (PCI). However, in the current era, with the development of new techniques and tools, experienced operators can perform CTO-PCI successfully in the majority of patients. The current indications and benefit of CTO-PCI remain a topic of controversy and debate. There is a growing body of predominantly nonrandomized studies reporting both short-term and long-term outcomes of CTO-PCI. Recent and upcoming randomized-controlled trials in this area will also potentially expand indications in both stable and patients with acute coronary syndrome. In this review, we will discuss the current evidence for CTO-PCI and also future directions in this field.

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