Scheduled meal accelerates entrainment to a 6-h phase advance by shifting central and peripheral oscillations in rats
- PMID: 28661071
- DOI: 10.1111/ejn.13633
Scheduled meal accelerates entrainment to a 6-h phase advance by shifting central and peripheral oscillations in rats
Abstract
Travelling across several time zones requires a fast adjustment of the circadian system and the differential adjustment speeds of organs and systems results in what is commonly referred as jet lag. During this transitory state of circadian disruption, individuals feel discomfort, appetite loss, fatigue, disturbed sleep and deficient performance of multiple tasks. We have demonstrated that after a 6-h phase advance of the light-dark cycle (LD) scheduled food in phase with the new night onset can speed up re-entrainment. In this study, we explored the possible mechanisms underlying the fast re-entrainment due to the feeding schedule. We focused on first- and second-order structures that provide metabolic information to the suprachiasmatic nucleus (SCN). We compared (i) control rats without change in LD cycle; (ii) rats exposed to a 6-h phase advance of the LD cycle with food ad libitum; and (iii) rats exposed to the 6-h phase advance combined with food access in phase with the new night. We found an immediate synchronizing effect of food on stomach distention and on c-Fos expression in the nucleus of the solitary tract, arcuate nucleus of the hypothalamus, dorsomedial hypothalamic nucleus and paraventricular nucleus. These observations indicate that in a model of jet lag, scheduled feeding can favour an immediate shift in first- and second-order relays to the SCN and that by keeping feeding schedules coupled to the new night, a fast re-entrainment may be achieved by shifting peripheral and extra-SCN oscillations.
Keywords: chronotherapy; circadian rhythms; food entrainment; jet lag; suprachiasmatic nucleus.
© 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.
Similar articles
-
Chocolate for breakfast prevents circadian desynchrony in experimental models of jet-lag and shift-work.Sci Rep. 2020 Apr 10;10(1):6243. doi: 10.1038/s41598-020-63227-w. Sci Rep. 2020. PMID: 32277140 Free PMC article.
-
Scheduled food hastens re-entrainment more than melatonin does after a 6-h phase advance of the light-dark cycle in rats.J Biol Rhythms. 2011 Aug;26(4):324-34. doi: 10.1177/0748730411409715. J Biol Rhythms. 2011. PMID: 21775291
-
Unpredictable feeding schedules unmask a system for daily resetting of behavioural and metabolic food entrainment.Eur J Neurosci. 2007 Nov;26(10):2804-14. doi: 10.1111/j.1460-9568.2007.05893.x. Eur J Neurosci. 2007. PMID: 18001277
-
From circadian clock mechanism to sleep disorders and jet lag: Insights from a computational approach.Biochem Pharmacol. 2021 Sep;191:114482. doi: 10.1016/j.bcp.2021.114482. Epub 2021 Feb 20. Biochem Pharmacol. 2021. PMID: 33617843 Review.
-
Scheduled meals and scheduled palatable snacks synchronize circadian rhythms: consequences for ingestive behavior.Physiol Behav. 2011 Sep 26;104(4):555-61. doi: 10.1016/j.physbeh.2011.05.001. Epub 2011 May 10. Physiol Behav. 2011. PMID: 21565213 Review.
Cited by
-
Timed restricted feeding cycles drive daily rhythms in female rats maintained in constant light but only partially restore the estrous cycle.Front Nutr. 2022 Sep 20;9:999156. doi: 10.3389/fnut.2022.999156. eCollection 2022. Front Nutr. 2022. PMID: 36204367 Free PMC article.
-
Cyrcadian Rhythm, Mood, and Temporal Patterns of Eating Chocolate: A Scoping Review of Physiology, Findings, and Future Directions.Nutrients. 2022 Jul 28;14(15):3113. doi: 10.3390/nu14153113. Nutrients. 2022. PMID: 35956290 Free PMC article. Review.
-
Impact of Time-Restricted Feeding on Adaptation to a 6-Hour Delay Phase Shift or a 12-Hour Phase Shift in Mice.Nutrients. 2022 Jul 23;14(15):3025. doi: 10.3390/nu14153025. Nutrients. 2022. PMID: 35893879 Free PMC article.
-
Phasic Neuronal Firing in the Rodent Nucleus of the Solitary Tract ex vivo.Front Physiol. 2021 Mar 2;12:638695. doi: 10.3389/fphys.2021.638695. eCollection 2021. Front Physiol. 2021. PMID: 33762969 Free PMC article.
-
Impact of Time-Restricted Feeding to Late Night on Adaptation to a 6 h Phase Advance of the Light-Dark Cycle in Mice.Front Physiol. 2021 Feb 16;12:634187. doi: 10.3389/fphys.2021.634187. eCollection 2021. Front Physiol. 2021. PMID: 33664675 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials