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Review
. 2017 May 2;25(5):1000-1011.
doi: 10.1016/j.cmet.2017.04.018.

The Limits of Exercise Physiology: From Performance to Health

Brendan M Gabriel  1 , Juleen R Zierath  2
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Free article
Review

The Limits of Exercise Physiology: From Performance to Health

Brendan M Gabriel et al. Cell Metab. .
Free article

Abstract

Many of the established positive health benefits of exercise have been documented by historical discoveries in the field of exercise physiology. These investigations often assess limits: the limits of performance, or the limits of exercise-induced health benefits. Indeed, several key findings have been informed by studying highly trained athletes, in addition to healthy or unhealthy people. Recent progress has been made in regard to skeletal muscle metabolism and personalized exercise regimes. In this perspective, we review some of the historical milestones of exercise physiology, discuss how these inform contemporary knowledge, and speculate on future questions.

Keywords: circadian rhythm; exercise physiology; exercise training; mitochondria; skeletal muscle; trainability.

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