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Review
. 2017 Jul;20(4):286-293.
doi: 10.1097/MCO.0000000000000378.

Prevention of metabolic diseases: fruits (including fruit sugars) vs. vegetables

Affiliations
Review

Prevention of metabolic diseases: fruits (including fruit sugars) vs. vegetables

Jessica N Kuzma et al. Curr Opin Clin Nutr Metab Care. 2017 Jul.

Abstract

Purpose of review: To discuss recent evidence from observational and intervention studies on the relationship between fruit and vegetable (F&V) consumption and metabolic disease.

Recent findings: Observational studies have consistently demonstrated a modest inverse association between the intake of fruit and leafy green vegetables, but not total vegetables, and biomarkers of metabolic disease as well as incident type 2 diabetes mellitus. This is in contrast to limited evidence from recently published randomized controlled dietary intervention trials, which - in sum - suggests little to no impact of increased F&V consumption on biomarkers of metabolic disease.

Summary: Evidence from observational studies that fruit and leafy green vegetable intake is associated with lower type 2 diabetes risk and better metabolic health could not be confirmed by dietary intervention trials. It is unclear whether this discrepancy is because of limitations inherent in observational studies (e.g., subjective dietary assessment methods, residual confounding) or due to limitations in the few available intervention studies (e.g., short duration of follow-up, interventions combining whole fruit and fruit juice, or lack of compliance). Future studies that attempt to address these limitations are needed to provide more conclusive insight into the impact of F&V consumption on metabolic health.

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References

    1. Guariguata L, Whiting DR, Hambleton I, et al. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract. 2014;103(2):137–49. - PubMed
    1. Kolderup A, Svihus B. Fructose metabolism and relation to atherosclerosis, type 2 diabetes, and obesity. J Nutr Metab. 2015;2015:823081. - PMC - PubMed
    1. Wang PY, Fang JC, Gao ZH, et al. Higher intake of fruits, vegetables or their fiber reduces the risk of type 2 diabetes: A meta-analysis. J Diabetes Investig. 2016;7(1):56–69. This is the most recent meta-analysis of observational studies assessing the relationship between fruit and vegetable intake, incident type 2 diabetes mellitus, and metabolic disease. These authors concluded that higher intakes of fruit and leafy green vegetables were associated with lower risk of T2DM. - PMC - PubMed
    1. Wallace IR, McEvoy CT, Hunter SJ, et al. Dose-response effect of fruit and vegetables on insulin resistance in people at high risk of cardiovascular disease: a randomized controlled trial. Diabetes Care. 2013;36(12):3888–96. - PMC - PubMed
    1. Cook LT, O’Reilly GA, Goran MI, et al. Vegetable consumption is linked to decreased visceral and liver fat and improved insulin resistance in overweight Latino youth. J Acad Nutr Diet. 2014;114(11):1776–83. - PMC - PubMed