Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017:2017:7589184.
doi: 10.1155/2017/7589184. Epub 2017 Feb 9.

Medication Adherence Mediates the Association between Type D Personality and High HbA1c Level in Chinese Patients with Type 2 Diabetes Mellitus: A Six-Month Follow-Up Study

Xuemei Li  1 , Min Gao  2 , Shengfa Zhang  2 , Huiwen Xu  3 , Huixuan Zhou  2 , Xiaohua Wang  2 , Zhiyong Qu  2 , Jing Guo  4 , Weijun Zhang  2 , Donghua Tian  2
Affiliations

Medication Adherence Mediates the Association between Type D Personality and High HbA1c Level in Chinese Patients with Type 2 Diabetes Mellitus: A Six-Month Follow-Up Study

Xuemei Li et al. J Diabetes Res. 2017.

Abstract

Aims. To examine the association between Type D personality and HbA1c level and to explore the mediating role of medication adherence between them in patients with type 2 diabetes mellitus (T2DM). Methods. 330 patients went on to complete a self-report measure of medication adherence and the HbA1c tests. Chi-square test, T test, Ordinary Least Square Regression (OLS), and Recentered Influence Function Regression (RIF) were employed. Results. Patients with Type D personality had significantly higher HbA1c value (P < 0.01). When Type D personality was operationalized as a categorical variable, SI was associated with HbA1c (P < 0.01). When NA, SI, and their interaction term were entered into regression, all of them were no longer associated with HbA1c level (P > 0.1). On the other hand, when Type D personality was operationalized as a continuous variable, only SI trait was associated with HbA1c level (P < 0.01). When NA, SI, and NA × SI term together were entered into regression, only SI was not related to HbA1c level. Furthermore, medication adherence had a significant mediation effect between Type D personality and HbA1c, accounting for 54.43% of the total effect. Conclusion. Type D personality was associated with HbA1c in direct and indirect ways, and medication adherence acted as a mediator role.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Medication adherence as a mediator between Type D personality and Type D personality after discharge. Note: A path: the independent variable (Type D personality) significantly influences the dependent variable (HbA1c level at T2) in the absence of the mediator (medication adherence). B path: the mediator (medication adherence) has a significant unique effect on the dependent variable (HbA1c level at T2) and also means that the direct effect of medication adherence on the dependent variable (HbA1c level at T2). C path: the independent variable (Type D personality) significantly influences the dependent variable (HbA1c level at T2). C′ path: the independent variable (Type D personality) significantly influences the dependent variable (HbA1c level at T2) on the addition of the mediator (medication adherence).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Burkhart P. V., Sabaté E. Adherence to long-term therapies: evidence for action. Journal of Nursing Scholarship. 2003;35(3):p. 207. - PubMed
    1. Liebl A., Neiß A., Spannheimer A., Reitberger U., Wagner T., Görtz A. Kosten des typ-2-diabetes in deutschland. Deutsche Medizinische Wochenschrift. 2001;126(20):585–589. doi: 10.1055/s-2001-14102. - DOI - PubMed
    1. Osterberg L., Blaschke T. Adherence to medication. The New England Journal of Medicine. 2005;353(5):487–497. doi: 10.1056/nejmra050100. - DOI - PubMed
    1. Williams L., O'Connor R. C., Grubb N., O'Carroll R. Type D personality predicts poor medication adherence in myocardial infarction patients. Psychology & Health. 2011;26(6):703–712. doi: 10.1080/08870446.2010.488265. - DOI - PubMed
    1. Molloy G. J., Randall G., Wikman A., Perkins-Porras L., Messerli-Bürgy N., Steptoe A. Type D personality, self-efficacy, and medication adherence following an acute coronary syndrome. Psychosomatic Medicine. 2012;74(1):100–106. doi: 10.1097/PSY.0b013e31823a5b2f. - DOI - PubMed

Substances