Evaluation of the predictive value of placental vascularisation indices derived from 3-Dimensional power Doppler whole placental volume scanning for prediction of pre-eclampsia: A systematic review and meta-analysis
- PMID: 28089506
- DOI: 10.1016/j.placenta.2017.01.005
Evaluation of the predictive value of placental vascularisation indices derived from 3-Dimensional power Doppler whole placental volume scanning for prediction of pre-eclampsia: A systematic review and meta-analysis
Abstract
Pre-eclampsia remains a leading cause of maternal and fetal morbidity and mortality. This systematic review aims to evaluate the ability of placental vascularisation indices (PVIs) derived from 3D power Doppler whole placental volume scanning to predict early, late and any-onset pre-eclampsia (PE). The following databases were searched: MEDLINE, EMBASE and Web of Science. Studies selected for inclusion measured PVIs: Vascularisation Index (%) (VI) and/or Flow Index (FI) and/or Vascularisation Flow Index (VFI) derived from 3D power Doppler whole placental volume scanning via Virtual Organ Computer-aided Analysis (VOCAL) technique prior to diagnosis of PE. A total of 667 records were screened with five eligible studies included. A narrative review of all studies was undertaken and three studies with sufficient data were included in a meta-analysis. This review, the first of its kind to evaluate the predictive value of PVIs for PE, reports significantly lower first trimester PVIs across a range of studies in women who develop PE. Mean differences in vascularisation indices in PE and non-PE pregnancies were: VI -2.93% (95% CI -5.84,-0.01), FR -2.83 (95% CI -3.97,-1.69) and VFI -0.93 (95% CI -1.6,-0.25), respectively. While only two studies reported sensitivity and specificity data, VI and VFI most accurately predicted early onset PE, and VFI predicted PE in high risk women. Further research is required to validate these findings in different study populations and to examine the performance of PVIs within combined screening models for PE.
Keywords: 3D power Doppler; Placental vascularisation indices; Pre-eclampsia; Prediction.
Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.
Similar articles
-
Placental vascularization indices and prediction of pre-eclampsia in high-risk women.Placenta. 2018 Oct;70:53-59. doi: 10.1016/j.placenta.2018.09.005. Epub 2018 Sep 13. Placenta. 2018. PMID: 30316328
-
Ophthalmic artery Doppler for prediction of pre-eclampsia: systematic review and meta-analysis.Ultrasound Obstet Gynecol. 2018 Jun;51(6):731-737. doi: 10.1002/uog.19002. Epub 2018 May 3. Ultrasound Obstet Gynecol. 2018. PMID: 29330892 Review.
-
Utero-placental vascularisation in normal and preeclamptic and intra-uterine growth restriction pregnancies: third trimester quantification using 3D power Doppler with comparison to placental vascular morphology (EVUPA): a prospective controlled study.BMJ Open. 2016 Mar 31;6(3):e009909. doi: 10.1136/bmjopen-2015-009909. BMJ Open. 2016. PMID: 27033959 Free PMC article. Clinical Trial.
-
Placental volume, vasculature and calcification in pregnancies complicated by pre-eclampsia and intra-uterine growth restriction.Eur J Obstet Gynecol Reprod Biol. 2015 Dec;195:12-17. doi: 10.1016/j.ejogrb.2015.07.023. Epub 2015 Aug 7. Eur J Obstet Gynecol Reprod Biol. 2015. PMID: 26461962
-
[Placental 3D Doppler angiography: current and upcoming applications].J Gynecol Obstet Biol Reprod (Paris). 2015 Feb;44(2):107-18. doi: 10.1016/j.jgyn.2014.09.007. Epub 2014 Oct 11. J Gynecol Obstet Biol Reprod (Paris). 2015. PMID: 25307617 Review. French.
Cited by
-
B-Flow/Spatiotemporal Image Correlation M-Mode and Contrast-Enhanced/Microbubble Ultrasonography Quantification of Spiral Artery Distensibility and Placental Intervillous Perfusion in the First Trimester in a Primate Model of Impaired Spiral Artery Remodeling.Ultrasound Med Biol. 2023 Dec;49(12):2557-2564. doi: 10.1016/j.ultrasmedbio.2023.08.021. Epub 2023 Sep 24. Ultrasound Med Biol. 2023. PMID: 37749012
-
Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy.Metabolites. 2023 May 31;13(6):715. doi: 10.3390/metabo13060715. Metabolites. 2023. PMID: 37367874 Free PMC article.
-
Application of Color Doppler with 3- and 4-Dimensional Ultrasonography in the Prenatal Evaluation of Fetal Extracardiac and Placental Abnormalities.Healthcare (Basel). 2023 Feb 8;11(4):488. doi: 10.3390/healthcare11040488. Healthcare (Basel). 2023. PMID: 36833022 Free PMC article. Review.
-
First-trimester maternal haemodynamic adaptation to pregnancy and placental, embryonic and fetal development: the prospective observational Rotterdam Periconception cohort.BJOG. 2022 Apr;129(5):785-795. doi: 10.1111/1471-0528.16979. Epub 2021 Nov 2. BJOG. 2022. PMID: 34665928 Free PMC article.
-
A 10-Year Retrospective Review of Prenatal Applications, Current Challenges and Future Prospects of Three-Dimensional Sonoangiography.Diagnostics (Basel). 2021 Aug 21;11(8):1511. doi: 10.3390/diagnostics11081511. Diagnostics (Basel). 2021. PMID: 34441444 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical