Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women
- PMID: 27820938
- DOI: 10.1159/000452660
Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women
Abstract
Background/aims: To estimate the prevalence of diagnosed endometriosis (DE) in women in the United States and assess the associated symptomatic burden.
Methods: An online, cross-sectional survey of women aged 18-49 years was conducted from August 6, 2012, through November 14, 2012. Survey data (weighted by age, race, education, income, geographical distribution, and propensity score) were used to estimate the prevalence and symptomatic burden of DE in women in the United States. Weighted logistic regressions were used to assess differences in symptom burden between women with and without endometriosis.
Results: The prevalence of DE was estimated at 6.1% (2,922 of 48,020 women surveyed); 52.7% of women were 18-29 years of age when they were diagnosed with endometriosis. Most (86.2%) women experienced symptoms before diagnosis. More women with (vs. without) DE had menstrual pelvic pain/cramping (52.7 vs. 45.2%), non-menstrual pelvic pain/cramping (36.7 vs. 14.3%), infertility (11.6 vs. 3.4%), and dyspareunia (29.5 vs. 13.4%). Women with endometriosis were also more likely to report severe symptoms (OR (95% CI) 2.7 (2.3-3.1) for menstrual pelvic pain/cramping, 2.2 (1.7-2.9) for non-menstrual pelvic pain/cramping, and 2.4 (1.8-3.2) for dyspareunia).
Conclusion: The prevalence of DE among US women is notable, and affected women experience a substantial symptom burden.
Keywords: Cross-sectional survey; Endometriosis; Prevalence; Symptoms.
© 2016 S. Karger AG, Basel.
Similar articles
-
Prevalence, Symptomatic Burden, and Diagnosis of Endometriosis in Canada: Cross-Sectional Survey of 30 000 Women.J Obstet Gynaecol Can. 2020 Jul;42(7):829-838. doi: 10.1016/j.jogc.2019.10.038. Epub 2020 Jan 27. J Obstet Gynaecol Can. 2020. PMID: 32001176
-
Endometriosis and associated symptoms among Nigerian women.Int J Gynaecol Obstet. 2015 Aug;130(2):190-4. doi: 10.1016/j.ijgo.2015.02.030. Epub 2015 Apr 24. Int J Gynaecol Obstet. 2015. PMID: 25935474
-
The burden of endometriosis symptoms on health-related quality of life in women in the United States: a cross-sectional study.J Psychosom Obstet Gynaecol. 2017 Dec;38(4):238-248. doi: 10.1080/0167482X.2017.1289512. Epub 2017 Feb 21. J Psychosom Obstet Gynaecol. 2017. PMID: 28635533
-
Prevalence of endometriosis diagnosed by laparoscopy in adolescents with dysmenorrhea or chronic pelvic pain: a systematic review.Hum Reprod Update. 2013 Sep-Oct;19(5):570-82. doi: 10.1093/humupd/dmt016. Epub 2013 May 31. Hum Reprod Update. 2013. PMID: 23727940 Review.
-
[Endometriosis : An often unrecognized pain disorder].Schmerz. 2016 Oct;30(5):477-490. doi: 10.1007/s00482-016-0154-1. Schmerz. 2016. PMID: 27681777 Review. German.
Cited by
-
Immune pathway through endometriosis to ovarian cancer.World J Clin Oncol. 2024 Apr 24;15(4):496-522. doi: 10.5306/wjco.v15.i4.496. World J Clin Oncol. 2024. PMID: 38689629 Free PMC article. Review.
-
Presence of endometriosis and chronic overlapping pain conditions negatively impacts the pain experience in women with chronic pelvic-abdominal pain: A cross-sectional survey.Womens Health (Lond). 2024 Jan-Dec;20:17455057241248017. doi: 10.1177/17455057241248017. Womens Health (Lond). 2024. PMID: 38682290 Free PMC article.
-
Endometriosis-Related Ovarian Cancer: Where Are We Now? A Narrative Review towards a Pragmatic Approach.J Clin Med. 2024 Mar 27;13(7):1933. doi: 10.3390/jcm13071933. J Clin Med. 2024. PMID: 38610698 Free PMC article. Review.
-
Evaluation of HLA-DQ2 and HLA-DQ8 haplotypes in patients with endometriosis, A case-control study.Clinics (Sao Paulo). 2024 Mar 2;79:100317. doi: 10.1016/j.clinsp.2023.100317. eCollection 2024. Clinics (Sao Paulo). 2024. PMID: 38432123 Free PMC article.
-
Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis.J Pharm Anal. 2024 Jan;14(1):100-114. doi: 10.1016/j.jpha.2023.09.005. Epub 2023 Sep 11. J Pharm Anal. 2024. PMID: 38352946 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical