Aspirin for the Prevention of Preeclampsia and Intrauterine Growth Restriction
- PMID: 27235915
- DOI: 10.1016/j.cll.2016.01.013
Aspirin for the Prevention of Preeclampsia and Intrauterine Growth Restriction
Abstract
Low-dose aspirin (LDA) has been used for several years for the prevention of preeclampsia (PE). LDA started in early pregnancy is associated with improvement of placental implantation. The best evidence suggest that LDA can prevent more than half of PE cases in high-risk women when started before 16 weeks of gestation. Moreover, LDA started in early pregnancy reduces the risk of other placenta-mediated complications such as intrauterine growth restriction (IUGR) and perinatal death. The efficacy of LDA has been demonstrated in women with abnormal first-trimester uterine artery Doppler or with prior history of chronic hypertension or preeclampsia.
Keywords: Aspirin; Intrauterine growth restriction; Placenta; Preeclampsia; Pregnancy.
Copyright © 2016 Elsevier Inc. All rights reserved.
Similar articles
-
Usefulness of aspirin therapy in high-risk pregnant women with abnormal uterine artery Doppler ultrasound at 14-16 weeks pregnancy: randomized controlled clinical trial.Croat Med J. 2005 Oct;46(5):826-31. Croat Med J. 2005. PMID: 16158479 Clinical Trial.
-
Acetylsalicylic acid for the prevention of preeclampsia and intra-uterine growth restriction in women with abnormal uterine artery Doppler: a systematic review and meta-analysis.J Obstet Gynaecol Can. 2009 Sep;31(9):818-826. doi: 10.1016/S1701-2163(16)34300-6. J Obstet Gynaecol Can. 2009. PMID: 19941706 Review.
-
An open-label randomized-controlled trial of low dose aspirin with an early screening test for pre-eclampsia and growth restriction (TEST): Trial protocol.Contemp Clin Trials. 2016 Jul;49:143-8. doi: 10.1016/j.cct.2016.07.003. Epub 2016 Jul 6. Contemp Clin Trials. 2016. PMID: 27394381 Clinical Trial.
-
Low-molecular-weight heparin for prevention of preeclampsia and other placenta-mediated complications: a systematic review and meta-analysis.Am J Obstet Gynecol. 2022 Feb;226(2S):S1126-S1144.e17. doi: 10.1016/j.ajog.2020.11.006. Epub 2021 Apr 20. Am J Obstet Gynecol. 2022. PMID: 34301348
-
The role of aspirin, heparin, and other interventions in the prevention and treatment of fetal growth restriction.Am J Obstet Gynecol. 2018 Feb;218(2S):S829-S840. doi: 10.1016/j.ajog.2017.11.565. Epub 2017 Dec 8. Am J Obstet Gynecol. 2018. PMID: 29229321 Review.
Cited by
-
Gut Microbiota, Inflammation, and Probiotic Supplementation in Fetal Growth Restriction-A Comprehensive Review of Human and Animal Studies.Life (Basel). 2023 Nov 21;13(12):2239. doi: 10.3390/life13122239. Life (Basel). 2023. PMID: 38137841 Free PMC article. Review.
-
Potential adverse actions of prenatal exposure of acetaminophen to offspring.Front Pharmacol. 2023 Apr 5;14:1094435. doi: 10.3389/fphar.2023.1094435. eCollection 2023. Front Pharmacol. 2023. PMID: 37089952 Free PMC article. Review.
-
Effects of Low-Dose Aspirin Combined with Vitamin E on the Incidence of Intrauterine Growth Restriction and Hemorheological Indexes of Pregnant Women in Patients with Gestational Hypertension.Comput Math Methods Med. 2022 Feb 21;2022:6328807. doi: 10.1155/2022/6328807. eCollection 2022. Comput Math Methods Med. 2022. Retraction in: Comput Math Methods Med. 2023 Jun 28;2023:9898473. doi: 10.1155/2023/9898473. PMID: 35237342 Free PMC article. Retracted. Clinical Trial.
-
Identification of female-specific risk enhancers throughout the lifespan of women to improve cardiovascular disease prevention.Am J Prev Cardiol. 2020 Jun 6;2:100028. doi: 10.1016/j.ajpc.2020.100028. eCollection 2020 Jun. Am J Prev Cardiol. 2020. PMID: 34327455 Free PMC article. Review.
-
Aspirin Desensitization: Implications for Acetylsalicylic Acid-Sensitive Pregnant Women.Medicina (Kaunas). 2021 Apr 17;57(4):390. doi: 10.3390/medicina57040390. Medicina (Kaunas). 2021. PMID: 33920569 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
