Noradrenaline effects on social behaviour, intergroup relations, and moral decisions
- PMID: 27126289
- PMCID: PMC4899514
- DOI: 10.1016/j.neubiorev.2016.03.031
Noradrenaline effects on social behaviour, intergroup relations, and moral decisions
Abstract
Recent research has begun to elucidate the neural basis of higher order social concepts, such as the mechanisms involved in intergroup relations, and moral judgments. Most theories have concentrated on higher order emotions, such as guilt, shame, or empathy, as core mechanisms. Accordingly, psychopharmacological and neurobiological studies have investigated the effects of manipulating serotonin or oxytocin activity on moral and social decisions and attitudes. However, recently it has been determined that changes in more basic emotions, such as fear and anger, might also have a significant role in social and moral cognition. This article summarizes psychopharmacological and fMRI research on the role of noradrenaline in higher order social cognition suggesting that indeed noradrenergic mediated affective changes might play key - and probably causal - role in certain social attitudes and moral judgments. Social judgments may also be directly influenced by numerous neurotransmitter manipulations but these effects could be mediated by modulation of basic emotions which appear to play an essential role in the formation of social concepts and moral behaviour.
Copyright © 2016. Published by Elsevier Ltd.
Figures
![Fig. 1](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/4899514/bin/gr1.gif)
![Fig. 2](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/4899514/bin/gr2.gif)
Similar articles
-
Moral emotions and moral behavior.Annu Rev Psychol. 2007;58:345-72. doi: 10.1146/annurev.psych.56.091103.070145. Annu Rev Psychol. 2007. PMID: 16953797 Free PMC article.
-
The rise of moral emotions in neuropsychiatry.Dialogues Clin Neurosci. 2015 Dec;17(4):411-20. doi: 10.31887/DCNS.2015.17.4/lfontenelle. Dialogues Clin Neurosci. 2015. PMID: 26869842 Free PMC article. Review.
-
[The Recognition of Emotions, Empathy and Moral Judgment in the National Mental Health Survey in Colombia, 2015].Rev Colomb Psiquiatr. 2016 Dec;45 Suppl 1:96-104. doi: 10.1016/j.rcp.2016.04.004. Epub 2016 Jun 8. Rev Colomb Psiquiatr. 2016. PMID: 27993262 Spanish.
-
[The contribution of neuroscience to the understanding of moral behavior].Rev Med Chil. 2009 Mar;137(3):419-25. Epub 2009 Jun 15. Rev Med Chil. 2009. PMID: 19621186 Spanish.
-
Emotion, regulation, and moral development.Annu Rev Psychol. 2000;51:665-97. doi: 10.1146/annurev.psych.51.1.665. Annu Rev Psychol. 2000. PMID: 10751984 Review.
Cited by
-
Negative emotionality downregulation affects moral choice but not moral judgement of harm: a pharmacological study.Sci Rep. 2024 Jan 12;14(1):1200. doi: 10.1038/s41598-024-51345-8. Sci Rep. 2024. PMID: 38216629 Free PMC article.
-
Maternal exposure to SSRIs or SNRIs and the risk of congenital abnormalities in offspring: A systematic review and meta-analysis.PLoS One. 2023 Nov 29;18(11):e0294996. doi: 10.1371/journal.pone.0294996. eCollection 2023. PLoS One. 2023. PMID: 38019759 Free PMC article.
-
Effects of bariatric surgery and dietary interventions for obesity on brain neurotransmitter systems and metabolism: A systematic review of positron emission tomography (PET) and single-photon emission computed tomography (SPECT) studies.Obes Rev. 2023 Nov;24(11):e13620. doi: 10.1111/obr.13620. Epub 2023 Sep 12. Obes Rev. 2023. PMID: 37699864 Free PMC article. Review.
-
Effect of Gabapentin-Fluoxetine Derivative GBP1F in a Murine Model of Depression, Anxiety and Cognition.Drug Des Devel Ther. 2023 Jun 16;17:1793-1803. doi: 10.2147/DDDT.S407229. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 37346999 Free PMC article.
-
The Microbiota-Gut Axis in Premature Infants: Physio-Pathological Implications.Cells. 2022 Jan 23;11(3):379. doi: 10.3390/cells11030379. Cells. 2022. PMID: 35159189 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources