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Review
. 2016 Feb;18(2):20.
doi: 10.1007/s11920-015-0655-0.

Prevention of Post-Traumatic Stress Disorder After Trauma: Current Evidence and Future Directions

Wei Qi  1 , Martin Gevonden  2 , Arieh Shalev  3
Affiliations
Review

Prevention of Post-Traumatic Stress Disorder After Trauma: Current Evidence and Future Directions

Wei Qi et al. Curr Psychiatry Rep. 2016 Feb.

Abstract

Post-traumatic stress disorder (PTSD) is a frequent, tenacious, and disabling consequence of traumatic events. The disorder's identifiable onset and early symptoms provide opportunities for early detection and prevention. Empirical findings and theoretical models have outlined specific risk factors and pathogenic processes leading to PTSD. Controlled studies have shown that theory-driven preventive interventions, such as cognitive behavioral therapy (CBT), or stress hormone-targeted pharmacological interventions, are efficacious in selected samples of survivors. However, the effectiveness of early clinical interventions remains unknown, and results obtained in aggregates (large groups) overlook individual heterogeneity in PTSD pathogenesis. We review current evidence of PTSD prevention and outline the need to improve the disorder's early detection and intervention in individual-specific paths to chronic PTSD.

Keywords: Cognitive behavioral therapy; Early treatment; Pharmacotherapy; Post-traumatic stress disorder; Prevention; Targeted intervention.

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Figures

Fig. 1
Fig. 1
Prevention targets for post-traumatic psychopathology. The bottom arrow represents a timeline from pre-to post-trauma. Psychosocial factors and neural-biological mechanisms represent groups of potential targets for intervention. formula image indicates interventions targeting specific elements
See this image and copyright information in PMC

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References

    1. Heron-Delaney M, Kenardy J, Charlton E, Matsuoka Y. A systematic review of predictors of posttraumatic stress disorder (PTSD) for adult road traffic crash survivors. Injury. 2013;44(11):1413–22. doi: 10.1016/j.injury.2013.07.011. - DOI - PubMed
    1. Seal KH, Bertenthal D, Miner CR, Sen S, Marmar C. Bringing the war back home: mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at department of veterans affairs facilities. Arch Intern Med. 2007;167(5):476–82. doi: 10.1001/archinte.167.5.476. - DOI - PubMed
    1. Marmar CR, Schlenger W, Henn-Haase C, et al. Course of posttraumatic stress disorder 40 years after the Vietnam war: findings from the national Vietnam veterans longitudinal study. JAMA Psychiatry. 2015;72(9):875–81. doi: 10.1001/jamapsychiatry.2015.0803. - DOI - PubMed
    1. Zatzick DF, Marmar CR, Weiss DS, et al. Posttraumatic stress disorder and functioning and quality of life outcomes in a nationally representative sample of male Vietnam veterans. Am J Psychiatr. 1997;154(12):1690–5. doi: 10.1176/ajp.154.12.1690. - DOI - PubMed
    1. Gallagher MW, Brown TA. Bayesian analysis of current and lifetime comorbidity rates of mood and anxiety disorders in individuals with posttraumatic stress disorder. J Psychopathol Behav Assess. 2015;37(1):60–6. doi: 10.1007/s10862-014-9436-z. - DOI - PMC - PubMed

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