Radiation induced liver disease: A clinical update
- PMID: 26300327
- DOI: 10.1016/j.jnci.2015.08.001
Radiation induced liver disease: A clinical update
Abstract
Radiation-induced liver disease (RILD) or radiation hepatitis is a sub-acute form of liver injury due to radiation. It is one of the most dreaded complications of radiation which prevents radiation dose escalation and re-irradiation for hepatobiliary or upper gastrointestinal malignancies. This complication should be kept in mind whenever a patient is planned for irradiation of these malignancies. Although, incidence of RILD is decreasing due to better knowledge of liver tolerance, improved investigation modalities and modern radiation delivery techniques, treatment options are still limited. In this review article, we have focussed on patho-physiology, risk factors, prevention and management of RILD.
Keywords: Management; Patho-physiology; Radiation induced liver disease; Risk factors.
Copyright © 2015 The Authors. Production and hosting by Elsevier B.V. All rights reserved.
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