Dietary Patterns Modulate the Risk of Non-Alcoholic Fatty Liver Disease in Chinese Adults
- PMID: 26083112
- PMCID: PMC4488813
- DOI: 10.3390/nu7064778
Dietary Patterns Modulate the Risk of Non-Alcoholic Fatty Liver Disease in Chinese Adults
Abstract
Although previous studies reported the associations between the intakes of individual foods or nutrients and the risk of non-alcoholic fatty liver disease (NAFLD), the relationship between dietary patterns and NAFLD in the Chinese population has been rarely studied to date. This study aimed to investigate the associations between dietary patterns and the risk of NAFLD in a middle-aged Chinese population. The Study subjects were 999 Chinese adults aged 45-60 years in the Anhui province who participated in the Hefei Nutrition and Health Study. Dietary intake was collected by a semi-quantitative food frequency questionnaire. NAFLD was defined as the presence of moderate-severe hepatic steatosis (by B-ultrasonic examination); the absence of excessive alcohol use (>20 g day(-1) in men and 10 g day(-1) in women); no use of steatogenic medications within the past six months; no exposure to hepatotoxins; and no history of bariatric surgery. Log-binomial regression analysis was used to examine the association between dietary patterns and NAFLD with adjustment of potential confounding variables. Out of 999 participants, 345 (34.5%) were classified as having NAFLD. Four major dietary patterns were identified: "Traditional Chinese", "Animal food", "Grains-vegetables" and "High-salt" dietary patterns. After adjusting for potential confounders, subjects in the highest quartile of the "Animal food" pattern scores had greater prevalence ratio for NAFLD (prevalence ratio (PR) = 1.354; 95% confidence interval (CI): 1.063-1.724; p < 0.05) than did those in the lowest quartile. After adjustment for body mass index (BMI), compared with the lowest quartile of the "Grains-vegetables" pattern, the highest quartile had a lower prevalence ratio for NAFLD (PR = 0.777; 95% CI: 0.618-0.977, p < 0.05). However, the "traditional Chinese" and "high-salt" dietary patterns showed no association with the risk of NAFLD. Our findings indicated that the "Animal food" dietary pattern was associated with an increased risk of NAFLD.
Keywords: China; dietary patterns; factor analysis; non-alcoholic fatty liver disease.
Similar articles
-
Dietary Patterns, Foods, and Nutrients to Ameliorate Non-Alcoholic Fatty Liver Disease: A Scoping Review.Nutrients. 2023 Sep 14;15(18):3987. doi: 10.3390/nu15183987. Nutrients. 2023. PMID: 37764771 Free PMC article. Review.
-
Dietary patterns and risk of non-alcoholic fatty liver disease in adults: A prospective cohort study.Clin Nutr. 2021 Oct;40(10):5373-5382. doi: 10.1016/j.clnu.2021.08.021. Epub 2021 Sep 4. Clin Nutr. 2021. PMID: 34560608
-
An observational study on the association between major dietary patterns and non-alcoholic fatty liver disease in Chinese adolescents.Medicine (Baltimore). 2018 Apr;97(17):e0576. doi: 10.1097/MD.0000000000010576. Medicine (Baltimore). 2018. PMID: 29703050 Free PMC article.
-
Practical Dietary Recommendations for the Prevention and Management of Nonalcoholic Fatty Liver Disease in Adults.Adv Nutr. 2018 Jan 1;9(1):30-40. doi: 10.1093/advances/nmx007. Adv Nutr. 2018. PMID: 29438460 Free PMC article. Review.
-
Gender impacts on the correlations between nonalcoholic fatty liver disease and hypertension in a Chinese population aged 45-60 y.Clin Exp Hypertens. 2016;38(7):639-643. doi: 10.1080/10641963.2016.1182181. Epub 2016 Sep 28. Clin Exp Hypertens. 2016. PMID: 27680771
Cited by
-
Association of fish and meat consumption with non-alcoholic fatty liver disease: Guangzhou Biobank Cohort Study.BMC Public Health. 2023 Dec 6;23(1):2433. doi: 10.1186/s12889-023-17398-6. BMC Public Health. 2023. PMID: 38057730 Free PMC article.
-
Analysis of the association between dietary patterns and nonalcoholic fatty liver disease in a county in Guangxi.BMC Gastroenterol. 2023 Sep 13;23(1):309. doi: 10.1186/s12876-023-02864-7. BMC Gastroenterol. 2023. PMID: 37704944 Free PMC article.
-
The Association Between Dietary Intake of Sodium, Potassium, and Na:K Ratio with the Risk of NAFLD: A Case-Control Study Among Iranian Adults.Int J Prev Med. 2021 Dec 30;12:179. doi: 10.4103/ijpvm.IJPVM_343_20. eCollection 2021. Int J Prev Med. 2021. PMID: 37663398 Free PMC article.
-
Role of Oxidative Stress and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 in Nonalcoholic Fatty Liver Disease.Int J Mol Sci. 2023 Jul 10;24(14):11271. doi: 10.3390/ijms241411271. Int J Mol Sci. 2023. PMID: 37511031 Free PMC article. Review.
-
Higher Overall Intakes Are the Defining Feature of Dietary Intakes in NAFLD and Compared to the General Population.Nutrients. 2023 Jun 8;15(12):2669. doi: 10.3390/nu15122669. Nutrients. 2023. PMID: 37375573 Free PMC article.
References
-
- Hou X.H., Zhu Y.X., Lu H.J., Chen H.F., Li Q., Jiang S., Xiang K.S., Jia W.P. Non-alcoholic fatty liver disease’s prevalence and impact on alanine aminotransferase associated with metabolic syndrome in the chinese. J. Gastroenterol. Hepatol. 2011;26:722–730. doi: 10.1111/j.1440-1746.2010.06509.x. - DOI - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials
Miscellaneous