Sleep and epilepsy syndromes
- PMID: 25965811
- DOI: 10.1055/s-0035-1551574
Sleep and epilepsy syndromes
Abstract
Sleep and epilepsy have a close relationship. About 20% of patients suffer seizures only during the night, approximately 40% only during the day and approximately 35% during the day and night. In certain epilepsy syndromes, the occurrence of seizures is strongly related to sleep or awakening. Infantile spasms appear predominately on awakening, and hypsarrhythmia is sometimes visible only in sleep. Children with Panayiotopoulos syndrome or benign epilepsy with centrotemporal spikes (BECTS) have seizures mostly when asleep, and in both syndromes interictal spike waves are markedly accentuated in slow wave sleep. Electrical status epilepticus during slow sleep/continuous spike wave discharges during sleep (ESES/CSWS), atypical benign partial epilepsy, and Landau-Kleffner syndrome are epileptic encephalopathies with substantial behavioral and cognitive deficits, various seizures, and continuous spike-wave activity during non-rapid eye movement (NREM) sleep. The hallmark of juvenile myoclonic epilepsy and grand mal seizures on awakening are seizure symptoms within 2 hours after awakening, often provoked by sleep deprivation. Nocturnal frontal lobe epilepsy is sometimes mistaken for parasomnia. Differentiation is possible when the clinical symptoms and the frequency of the paroxysmal events per night and month are carefully observed and nocturnal video electroencephalography (EEG) performed. Sleep EEG recordings may be helpful in patients with suspected epilepsy and nonconclusive awake EEG. Depending on the clinical question, sleep recordings should be performed during nap (natural sleep or drug induced), during the night, or after sleep deprivation.
Georg Thieme Verlag KG Stuttgart · New York.
Similar articles
-
[Electroencephalography in status epilepticus in sleep (ESES) in various clinical pictures].Acta Med Croatica. 2005;59(1):69-74. Acta Med Croatica. 2005. PMID: 15813359 Croatian.
-
Sleep and epilepsy.Sleep Med Rev. 1999 Sep;3(3):201-17. doi: 10.1016/s1087-0792(99)90002-3. Sleep Med Rev. 1999. PMID: 15310475
-
[Efficacy of methylprednisolone therapy for electrical status epilepticus during sleep in children].Zhonghua Er Ke Za Zhi. 2014 Sep;52(9):678-82. Zhonghua Er Ke Za Zhi. 2014. PMID: 25476430 Chinese.
-
Sleep and prolonged epileptic activity (status epilepticus).Epilepsy Res Suppl. 1991;2:165-76. Epilepsy Res Suppl. 1991. PMID: 1760086 Review.
-
Idiopathic focal epilepsies: the "lost tribe".Epileptic Disord. 2016 Sep 1;18(3):252-88. doi: 10.1684/epd.2016.0839. Epileptic Disord. 2016. PMID: 27435520 Review. English.
Cited by
-
Continuous Spike-Waves during Slow Sleep Today: An Update.Children (Basel). 2024 Jan 28;11(2):169. doi: 10.3390/children11020169. Children (Basel). 2024. PMID: 38397281 Free PMC article. Review.
-
EEG-based spatiotemporal dynamics of fast ripple networks and hubs in infantile epileptic spasms.Epilepsia Open. 2024 Feb;9(1):122-137. doi: 10.1002/epi4.12831. Epub 2023 Nov 8. Epilepsia Open. 2024. PMID: 37743321 Free PMC article.
-
Genetic generalized and focal epilepsy prevalence in the North American SUDEP Registry.Neurology. 2020 Apr 21;94(16):e1757-e1763. doi: 10.1212/WNL.0000000000009295. Epub 2020 Mar 26. Neurology. 2020. PMID: 32217773 Free PMC article.
-
A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain.Dis Model Mech. 2019 Sep 12;12(9):dmm038828. doi: 10.1242/dmm.038828. Dis Model Mech. 2019. PMID: 31399478 Free PMC article.
-
Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model.Dis Model Mech. 2018 Dec 14;11(12):dmm036194. doi: 10.1242/dmm.036194. Dis Model Mech. 2018. PMID: 30467223 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials