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. 2014 May-Jun;66(3):280-8.
doi: 10.1016/j.ihj.2014.03.005. Epub 2014 Apr 16.

Cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians: a cross sectional study

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Cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians: a cross sectional study

Soneil Guptha et al. Indian Heart J. 2014 May-Jun.

Abstract

Objective: To determine levels of cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians.

Methods: Population based 6123 subjects (men 3388) were evaluated. Mean±1SD of various cholesterol lipoproteins (total, HDL, LDL and non-HDL cholesterol) and triglycerides were reported. Subjects were classified according to US National Cholesterol Education Program.

Results: Age-adjusted levels in men and women were cholesterol total 178.4 ± 39 and 184.6 ± 39, HDL 44.9 ± 11 and 51.1 ± 11, LDL 102.5 ± 33 and 106.2 ± 33, total:HDL 4.15 ± 1.2 and 3.79 ± 1.0 and triglycerides 162.5 ± 83 and 143.7 ± 83 mg/dl. Age-adjusted prevalence (%) in men and women, respectively were, total cholesterol ≥200 mg/dl 25.1 and 24.9, LDL cholesterol ≥130 mg/dl 16.3 and 15.1 and ≥100 mg/dl 49.5 and 49.7, HDL cholesterol <40/<50 mg/dl 33.6 and 52.8, total:HDL cholesterol ≥4.5 29.4 and 16.8, and triglycerides ≥150 mg/dl 42.1 and 32.9%. Cholesterol level was significantly greater in subjects with better socioeconomic status, body mass index and waist circumference while triglycerides were more among those with high socioeconomic status, fat intake, body mass index and waist circumference (p < 0.05). Hypercholesterolemia awareness (15.6%), treatment (7.2%) and control (4.1%) were low.

Conclusions: Mean cholesterol and LDL cholesterol are low and triglycerides were high in urban Asian Indians. Most prevalent dyslipidemias are borderline high LDL, low HDL and high triglycerides. Subjects with high socioeconomic status, high fat intake and greater adiposity have higher total and LDL cholesterol and triglyceride and lower HDL cholesterol.

Keywords: Atherogenic dyslipidemia; Cholesterol; Coronary heart disease; Epidemiology; Lipids.

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Figures

Fig. 1
Fig. 1
Age-group specific levels of total cholesterol, LDL cholesterol, triglycerides and HDL cholesterol (mg/dl). There is significant age-associated increase in total and LDL cholesterol (ANOVA trend, p < 0.001), more in women than men. Triglyceride levels are greater in younger men as compared to women with a significant age-associated increase. No significant trend is observed in HDL cholesterol levels.
Fig. 2
Fig. 2
Prevalence, awareness, treatment and control of hypercholesterolemia in the study subjects (age-adjusted percent values among as subjects with total cholesterol ≥200 mg/dl).

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