Cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians: a cross sectional study
- PMID: 24973832
- PMCID: PMC4121768
- DOI: 10.1016/j.ihj.2014.03.005
Cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians: a cross sectional study
Abstract
Objective: To determine levels of cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians.
Methods: Population based 6123 subjects (men 3388) were evaluated. Mean±1SD of various cholesterol lipoproteins (total, HDL, LDL and non-HDL cholesterol) and triglycerides were reported. Subjects were classified according to US National Cholesterol Education Program.
Results: Age-adjusted levels in men and women were cholesterol total 178.4 ± 39 and 184.6 ± 39, HDL 44.9 ± 11 and 51.1 ± 11, LDL 102.5 ± 33 and 106.2 ± 33, total:HDL 4.15 ± 1.2 and 3.79 ± 1.0 and triglycerides 162.5 ± 83 and 143.7 ± 83 mg/dl. Age-adjusted prevalence (%) in men and women, respectively were, total cholesterol ≥200 mg/dl 25.1 and 24.9, LDL cholesterol ≥130 mg/dl 16.3 and 15.1 and ≥100 mg/dl 49.5 and 49.7, HDL cholesterol <40/<50 mg/dl 33.6 and 52.8, total:HDL cholesterol ≥4.5 29.4 and 16.8, and triglycerides ≥150 mg/dl 42.1 and 32.9%. Cholesterol level was significantly greater in subjects with better socioeconomic status, body mass index and waist circumference while triglycerides were more among those with high socioeconomic status, fat intake, body mass index and waist circumference (p < 0.05). Hypercholesterolemia awareness (15.6%), treatment (7.2%) and control (4.1%) were low.
Conclusions: Mean cholesterol and LDL cholesterol are low and triglycerides were high in urban Asian Indians. Most prevalent dyslipidemias are borderline high LDL, low HDL and high triglycerides. Subjects with high socioeconomic status, high fat intake and greater adiposity have higher total and LDL cholesterol and triglyceride and lower HDL cholesterol.
Keywords: Atherogenic dyslipidemia; Cholesterol; Coronary heart disease; Epidemiology; Lipids.
Copyright © 2014 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
Figures
![Fig. 1](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/4121768/bin/gr1.gif)
![Fig. 2](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/4121768/bin/gr2.gif)
Similar articles
-
Trends in epidemiology of dyslipidemias in India.Indian Heart J. 2024 Mar;76 Suppl 1(Suppl 1):S20-S28. doi: 10.1016/j.ihj.2023.11.266. Epub 2024 Feb 12. Indian Heart J. 2024. PMID: 38360457 Free PMC article. Review.
-
Secular trends in cholesterol lipoproteins and triglycerides and prevalence of dyslipidemias in an urban Indian population.Lipids Health Dis. 2008 Oct 24;7:40. doi: 10.1186/1476-511X-7-40. Lipids Health Dis. 2008. PMID: 18950504 Free PMC article.
-
Prevalence of dyslipidemia and associated risk factors among Turkish adults: Trabzon lipid study.Endocrine. 2008 Aug-Dec;34(1-3):36-51. doi: 10.1007/s12020-008-9100-z. Epub 2008 Nov 12. Endocrine. 2008. PMID: 19003544
-
Cholesterol lipoproteins, triglycerides, rural-urban differences and prevalence of dyslipidaemia among males in Rajasthan.J Assoc Physicians India. 1997 Apr;45(4):275-9. J Assoc Physicians India. 1997. PMID: 12521083
-
Recent trends in epidemiology of dyslipidemias in India.Indian Heart J. 2017 May-Jun;69(3):382-392. doi: 10.1016/j.ihj.2017.02.020. Epub 2017 Mar 6. Indian Heart J. 2017. PMID: 28648438 Free PMC article. Review.
Cited by
-
Familial hypercholesterolemia.Indian Heart J. 2024 Mar;76 Suppl 1(Suppl 1):S108-S112. doi: 10.1016/j.ihj.2023.12.002. Epub 2024 Apr 8. Indian Heart J. 2024. PMID: 38599725 Free PMC article. Review.
-
Trends in epidemiology of dyslipidemias in India.Indian Heart J. 2024 Mar;76 Suppl 1(Suppl 1):S20-S28. doi: 10.1016/j.ihj.2023.11.266. Epub 2024 Feb 12. Indian Heart J. 2024. PMID: 38360457 Free PMC article. Review.
-
Indian dyslipidaemia guidelines: Need of the hour.Indian Heart J. 2024 Mar;76 Suppl 1(Suppl 1):S2-S5. doi: 10.1016/j.ihj.2024.01.008. Epub 2024 Jan 12. Indian Heart J. 2024. PMID: 38219904 Free PMC article. No abstract available.
-
Prediction of hypercholesterolemia using machine learning techniques.J Diabetes Metab Disord. 2022 Dec 22;22(1):255-265. doi: 10.1007/s40200-022-01125-w. eCollection 2023 Jun. J Diabetes Metab Disord. 2022. PMID: 37255802 Free PMC article.
-
High-density lipoproteins may play a crucial role in COVID-19.Virol J. 2022 Aug 23;19(1):135. doi: 10.1186/s12985-022-01865-4. Virol J. 2022. PMID: 35999545 Free PMC article.
References
-
- Burke G.L., Bell R.A. National and international trends in cardiovascular disease: incidence and risk factors. In: Blumenthal R.S., Foody J.M., Wong N.D., editors. Preventive Cardiology: A Companion to Braunwald's Heart Disease. Saunders-Elsevier; Philadelphia: 2011. pp. 14–32.
-
- Prospective Studies Collaboration. Lewington S., Whitlock G., Clarke R. Blood cholesterol and vascular mortality by age, sex and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet. 2007;370:1829–1839. - PubMed
-
- Zhang X., Patel A., Horibe H., Asia Pacific Cohort Studies Collaboration Cholesterol, coronary heart disease and stroke in the Asia Pacific region. Int J Epidemiol. 2003;32:563–572. - PubMed
-
- Fuster V., Kelly B.B., Board for Global Health . Institute of Medicine; Washington: 2010. Promoting Cardiovascular Health in Developing World: A Critical Challenge to Achieve Global Health. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical