The effect of green tea on blood pressure and lipid profile: a systematic review and meta-analysis of randomized clinical trials
- PMID: 24675010
- DOI: 10.1016/j.numecd.2014.01.016
The effect of green tea on blood pressure and lipid profile: a systematic review and meta-analysis of randomized clinical trials
Abstract
Introduction: Many different dietary supplements are currently marketed for the management of hypertension, but the evidence for effectiveness is mixed. The aim of this systematic review was to evaluate the evidence for or against the effectiveness of green tea (Camellia sinensis) on blood pressure and lipid parameters.
Methods and results: Electronic searches were conducted in Medline, Embase, Amed, Cinahl and the Cochrane Library to identify relevant human randomized clinical trials (RCTs). Hand searches of bibliographies were also conducted. The reporting quality of included studies was assessed using a checklist adapted from the CONSORT Statement. Two reviewers independently determined eligibility, assessed the reporting quality of the included studies, and extracted the data. As many as 474 citations were identified and 20 RCTs comprising 1536 participants were included. There were variations in the designs of the RCTs. A meta-analysis revealed a significant reduction in systolic blood pressure favouring green tea (MD: -1.94 mmHg; 95% CI: -2.95 to -0.93; I(2) = 8%; p = 0.0002). Similar results were also observed for total cholesterol (MD: -0.13 mmol/l; 95% CI: -0.2 to -0.07; I(2) = 8%; p < 0.0001) and LDL cholesterol (MD: -0.19 mmol/l; 95% CI: -0.3 to -0.09; I(2) = 70%; p = 0.0004). Adverse events included rash, elevated blood pressure, and abdominal discomfort.
Conclusion: Green tea intake results in significant reductions in systolic blood pressure, total cholesterol, and LDL cholesterol. The effect size on systolic blood pressure is small, but the effects on total and LDL cholesterol appear moderate. Longer-term independent clinical trials evaluating the effects of green tea are warranted.
Keywords: Blood lipid; Blood pressure; Green tea; Meta-analysis; Randomized clinical trial.
Copyright © 2014 Elsevier B.V. All rights reserved.
Similar articles
-
Effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials.Nutr Rev. 2015 Apr;73(4):236-46. doi: 10.1093/nutrit/nuv001. Nutr Rev. 2015. PMID: 26024546 Review.
-
Effect of the novel functional fibre, polyglycoplex (PGX), on body weight and metabolic parameters: A systematic review of randomized clinical trials.Clin Nutr. 2015 Dec;34(6):1109-14. doi: 10.1016/j.clnu.2015.01.004. Epub 2015 Jan 13. Clin Nutr. 2015. PMID: 25616600 Review.
-
Effect of the natural sweetener, steviol glycoside, on cardiovascular risk factors: a systematic review and meta-analysis of randomised clinical trials.Eur J Prev Cardiol. 2015 Dec;22(12):1575-87. doi: 10.1177/2047487314560663. Epub 2014 Nov 20. Eur J Prev Cardiol. 2015. PMID: 25412840 Review.
-
The effect of chlorogenic acid on blood pressure: a systematic review and meta-analysis of randomized clinical trials.J Hum Hypertens. 2015 Feb;29(2):77-81. doi: 10.1038/jhh.2014.46. Epub 2014 Jun 19. J Hum Hypertens. 2015. PMID: 24943289 Review.
-
Green and black tea for the primary prevention of cardiovascular disease.Cochrane Database Syst Rev. 2013 Jun 18;2013(6):CD009934. doi: 10.1002/14651858.CD009934.pub2. Cochrane Database Syst Rev. 2013. PMID: 23780706 Free PMC article. Review.
Cited by
-
The health benefits of rooibos tea in humans (aspalathus linearis)-a scoping review.J Public Health Afr. 2023 Dec 1;14(12):2784. doi: 10.4081/jphia.2023.2784. eCollection 2023 Dec 27. J Public Health Afr. 2023. PMID: 38204815 Free PMC article.
-
Green tea polyphenols alleviate di-(2-ethylhexyl) phthalate-induced liver injury in mice.World J Gastroenterol. 2023 Sep 14;29(34):5054-5074. doi: 10.3748/wjg.v29.i34.5054. World J Gastroenterol. 2023. PMID: 37753369 Free PMC article.
-
Supplements for Lipid Lowering: What Does the Evidence Show?Curr Cardiol Rep. 2023 Aug;25(8):795-805. doi: 10.1007/s11886-023-01903-9. Epub 2023 Jun 10. Curr Cardiol Rep. 2023. PMID: 37300664 Review.
-
Efficacy of Dietary Polyphenols from Whole Foods and Purified Food Polyphenol Extracts in Optimizing Cardiometabolic Health: A Meta-Analysis of Randomized Controlled Trials.Adv Nutr. 2023 Mar;14(2):270-282. doi: 10.1016/j.advnut.2023.01.002. Epub 2023 Feb 1. Adv Nutr. 2023. PMID: 36796437 Free PMC article. Review.
-
The effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis.Front Nutr. 2023 Jan 10;9:1084455. doi: 10.3389/fnut.2022.1084455. eCollection 2022. Front Nutr. 2023. PMID: 36704803 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials