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. 2011 May;73(3):255-61.
doi: 10.4103/0250-474X.93507.

Boswellia serrata, a potential antiinflammatory agent: an overview

M Z Siddiqui  1
Affiliations

Boswellia serrata, a potential antiinflammatory agent: an overview

M Z Siddiqui. Indian J Pharm Sci. 2011 May.

Abstract

The resin of Boswellia species has been used as incense in religious and cultural ceremonies and in medicines since time immemorial. Boswellia serrata (Salai/Salai guggul), is a moderate to large sized branching tree of family Burseraceae (Genus Boswellia), grows in dry mountainous regions of India, Northern Africa and Middle East. Oleo gum-resin is tapped from the incision made on the trunk of the tree and is then stored in specially made bamboo basket for removal of oil content and getting the resin solidified. After processing, the gum-resin is then graded according to its flavour, colour, shape and size. In India, the States of Andhra Pradesh, Gujarat, Madhya Pradesh, Jharkhand and Chhattisgarh are the main source of Boswellia serrata. Regionally, it is also known by different names. The oleo gum-resins contain 30-60% resin, 5-10% essential oils, which are soluble in the organic solvents, and the rest is made up of polysaccharides. Gum-resin extracts of Boswellia serrata have been traditionally used in folk medicine for centuries to treat various chronic inflammatory diseases. The resinous part of Boswellia serrata possesses monoterpenes, diterpenes, triterpenes, tetracyclic triterpenic acids and four major pentacyclic triterpenic acids i.e. β-boswellic acid, acetyl-β-boswellic acid, 11-keto-β-boswellic acid and acetyl-11-keto-β-boswellic acid, responsible for inhibition of pro-inflammatory enzymes. Out of these four boswellic acids, acetyl-11-keto-β-boswellic acid is the most potent inhibitor of 5-lipoxygenase, an enzyme responsible for inflammation.

Keywords: Agent; Boswellia serrata; Salai/Salai guggul; antiinflammatory; frankincense; olibanum; potential.

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Figures

Fig. 1
Fig. 1
Structures of four pentacyclic triterpenic acids (Boswellic acids) β-Boswellic acid, R1=H, R2=H2; acetyl-β-boswellic acid, R1=Ac, R2=H2; 11-keto-β-boswellic acid, R1=H, R2=O; acetyl-11-keto-β-boswellic acid, R1=Ac, R2=O.
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References

    1. Vol. 1. New Delhi: Council of Scientific and Industrial Research; 1948. Anon (CSIR). The Wealth of India, Raw Materials.
    1. Felter H, Lloyd J. I and II. Cincinnati: Ohio Valley Company, US; 1898. Kings American Dispensatory.
    1. Howes FN. Age-old resins of the Mediterranean region and their uses. Econ Bot. 1950;4:307–16.
    1. Krishnamurthy T, Shiva MP. Salai guggul (from Boswellia serrata Roxb.): Its exploitation and utilization. Indian Forest. 1977;103:466–74.
    1. Verghese J. Olibanum in focus. Perfumer Flavorist. 1988;13:2–11.

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