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Case Reports
. 2012 Jul;60(1):97-9.
doi: 10.1016/j.annemergmed.2011.11.018. Epub 2012 Jan 10.

Ketamine-like effects after recreational use of methoxetamine

Katharina E Hofer  1 , Bettina Grager, Daniel M Müller, Christine Rauber-Lüthy, Hugo Kupferschmidt, Katharina M Rentsch, Alessandro Ceschi
Affiliations
Case Reports

Ketamine-like effects after recreational use of methoxetamine

Katharina E Hofer et al. Ann Emerg Med. 2012 Jul.

Abstract

Methoxetamine, the N-ethyl derivative of ketamine, is a novel recreational drug that is not at present subject to restrictive regulations in most countries. To our knowledge, no case of methoxetamine abuse has been published to date in the scientific literature, and the only sources of information are illegal drug users' Web discussion forums. We report the first case of analytically confirmed intravenous methoxetamine abuse in a 19-year-old man. Observed signs and symptoms such as tachycardia, hypertension, confusion, agitation, stupor, ataxia, mydriasis, and nystagmus were consistent with ketamine-induced adverse effects and resolved with symptomatic treatment. According to this case report, user Web reports, and the chemical structure, methoxetamine produces ketamine-like effects. Complete recovery can be expected with supportive care.

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