Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 Jul-Aug;25(4):784-96.
doi: 10.1111/j.1939-1676.2011.0732.x. Epub 2011 May 12.

Idiopathic cystitis in domestic cats--beyond the lower urinary tract

C A T Buffington  1
Affiliations
Review

Idiopathic cystitis in domestic cats--beyond the lower urinary tract

C A T Buffington. J Vet Intern Med. 2011 Jul-Aug.

Abstract

Signs of lower urinary tract (LUT) disease in domestic cats can be acute or chronic, and can result from variable combinations of abnormalities within the lumen of the LUT, the parenchyma of the LUT itself, or other organ system(s) that then lead to LUT dysfunction. In the majority of cats with chronic signs of LUT dysfunction, no specific underlying cause can be confirmed after standard clinical evaluation of the LUT, so these cats typically are classified as having idiopathic cystitis. A syndrome in human beings commonly known as interstitial cystitis (IC) shares many features in common with these cats, permitting comparisons between the two species. A wide range of similarities in abnormalities has been identified between these syndromes outside as well as inside the LUT. A variety of potential familial and developmental risk factors also have been identified. These results have permitted generation of the hypothesis that some of these people have a disorder affecting the LUT rather than a disorder of the LUT. This perspective has suggested alternative diagnostic strategies and novel approaches to treatment, at least in cats. The purpose of this review is to summarize research investigations into the various abnormalities present in cats, to compare some of these findings with those identified in human beings, and to discuss how they might modify perceptions about the etiopathogenesis, diagnosis, and treatment of cats with this disease. Dedication: I dedicate this contribution to Professor Dennis J. Chew, whose collaboration, patience, and support made it all possible.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Westropp J, Buffington CAT. Lower urinary tract disorders in cats. In: Ettinger SJ, Feldman EC, editors. Textbook of Veterinary Internal Medicine. 7th ed. St. Louis, MO: Elsevier-Saunders; 2010. pp. 2069–2086.
    1. Osborne CA, Kruger JM, Lulich JP. Feline lower urinary tract disorders. Definition of terms and concepts. Vet Clin North Am Small Anim Pract. 1996;26:169–179. - PubMed
    1. Baranowski AP, Abrams P, Berger RE, et al. Urogenital pain-time to accept a new approach to phenotyping and, as a consequence, management. Eur Urol. 2008;53:33–36. - PubMed
    1. Hanno P, Lin A, Nordling J, et al. Bladder pain syndrome committee of the international consultation on incontinence. Neurourol Urodyn. 2010;29:191–198. - PubMed
    1. Buffington CA, Chew DJ, DiBartola SP. Interstitial cystitis in cats. Vet Clin North Am Small Anim Pract. 1996;26:317–326. - PubMed