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Review
. 2011 Mar;26(3):1099-101.
doi: 10.1093/ndt/gfq693. Epub 2010 Nov 15.

Renal transplantation for nephrogenic systemic fibrosis: a case report and review of the literature

Madison C Cuffy  1 , Mansher Singh, Richard Formica, Evans Simmons, Ali K Abu Alfa, Kacie Carlson, Michael Girardi, Shawn E Cowper, Sanjay Kulkarni
Affiliations
Review

Renal transplantation for nephrogenic systemic fibrosis: a case report and review of the literature

Madison C Cuffy et al. Nephrol Dial Transplant. 2011 Mar.

Abstract

Nephrogenic systemic fibrosis (NSF) is a rare fibrosing disorder described among patients with renal disease. Currently, no standard therapy exists, although therapeutic modalities have included plasmapheresis, extracorporeal photopheresis, sodium thiosulphate, imatinib and renal transplantation. We describe a patient with NSF who was physically debilitated and underwent renal transplantation. After transplantation, the patient's lesions improved clinically, and the patient was ambulatory. Despite developing worsening renal function, her lesions remained unchanged. We conclude that renal transplantation improves symptoms of NSF, and believe that in patients with NSF, careful consideration should be made for early renal transplantation.

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