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Review
. 2011:168:173-178.
doi: 10.1159/000321758. Epub 2010 Oct 7.

Clinical evaluation indices for hemodialysis/hemodiafiltration in Japan

Toshio Shinoda, Yutaka Koda
Review

Clinical evaluation indices for hemodialysis/hemodiafiltration in Japan

Toshio Shinoda et al. Contrib Nephrol. 2011.

Abstract

Japanese hemodialysis (HD) patients have two remarkable characteristics, that is they have a longer period of chronic HD and better clinical outcome than American and European HD patients. This might be partly explained by the very low prevalence of renal transplantation in Japan. As a result, younger HD patients without serious comorbid conditions, whose prognosis should be good, have not been transplanted but have been treated by chronic HD therapy for a long period. Other potential explanations might be higher prevalence of biocompatible high-flux membrane dialyzers and lower prevalence of arteriovenous graft in Japan than Western countries. Although online hemodiafiltration has potential advantage over high-flux HD, the impact of this therapy has not been evident because of its low prevalence in chronic dialysis therapy in Japan.

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