Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010;20(4):302-7.
doi: 10.2188/jea.je20090180. Epub 2010 Jun 5.

Epidemiologic features of Kawasaki disease in Japan: results of the 2007-2008 nationwide survey

Yosikazu Nakamura  1 , Mayumi Yashiro, Ritei Uehara, Atsuko Sadakane, Izumi Chihara, Yasuko Aoyama, Kazuhiko Kotani, Hiroshi Yanagawa
Affiliations

Epidemiologic features of Kawasaki disease in Japan: results of the 2007-2008 nationwide survey

Yosikazu Nakamura et al. J Epidemiol. 2010.

Abstract

Background: The most recent epidemiologic features of Kawasaki disease (KD) are unknown.

Methods: The 20th nationwide survey of KD was conducted in 2009, and included patients treated for the disease in 2007 and 2008. Hospitals specializing in pediatrics, and hospitals with pediatric departments and 100 or more beds, were asked to report all patients with KD during the 2 survey years.

Results: From a total of 1540 departments and hospitals, 23,337 patients (11 581 in 2007 and 11 756 in 2008) were reported: 13,523 boys and 9814 girls. The annual incidence rates were 215.3 and 218.6 per 100,000 children aged 0-4 years in 2007 and 2008, respectively. These were the highest annual KD incidence rates ever recorded in Japan. The monthly number of patients peaked during the winter months; smaller increases were noted in the summer months. The age-specific incidence rate showed a monomodal distribution with a peak at age 9-11 months. The prevalences of both cardiac lesions during the acute phase of the disease and cardiac sequelae were higher among infants and older age groups.

Conclusions: The incidence rate and number of patients with KD in Japan continue to increase.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. The number of patients with Kawasaki disease and incidence rate in Japan, by calendar year.
Figure 2.
Figure 2.. The number of patients with Kawasaki disease in Japan by month, 2001–2008.
Figure 3.
Figure 3.. Age-specific annual incidence rate of Kawasaki disease in Japan, 2007–2008.
Figure 4.
Figure 4.. Age-specific prevalence of cardiac lesions and sequelae due to Kawasaki disease in Japan, 2007–2008.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Burgner D , Harnden A. Kawasaki disease: What is the epidemiology telling us about the etiology? Int J Infect Dis. 2005;9:185–94 10.1016/j.ijid.2005.03.002 - DOI - PMC - PubMed
    1. Falcini F Kawasaki disease . Curr Opin Rheumatol. 2006;18:33–8 10.1097/01.bor.0000197998.50450.f6 - DOI - PubMed
    1. Pahlavan PS , Niroomand F. Coronary artery aneurysm: a review . Clin Cardiol. 2006;29:439–43 10.1002/clc.4960291005 - DOI - PMC - PubMed
    1. Imai Y , Sunagawa K , Ayusawa M , Miyashita M , Abe O , Suzuki J , et al. . A fatal case of ruptured giant coronary artery aneurysm . Eur J Pediatr. 2006;165:130–3 10.1007/s00431-005-0016-9 - DOI - PubMed
    1. Freeman AF , Crawford SE , Cornwall ML , Garcia FL , Shulman ST , Rowley AH. Angiogenesis in fatal acute Kawasaki disease coronary artery and myocardium . Pediatr Cardiol. 2005;26:578–84 10.1007/s00246-005-0801-2 - DOI - PubMed

Publication types