Hypoxic-ischemic encephalopathy in the term infant
- PMID: 19944838
- PMCID: PMC2849741
- DOI: 10.1016/j.clp.2009.07.011
Hypoxic-ischemic encephalopathy in the term infant
Abstract
Hypoxia-ischemia in the perinatal period is an important cause of cerebral palsy and associated disabilities in children. There has been significant research progress in hypoxic-ischemic encephalopathy over the last 2 decades, and many new molecular mechanisms have been identified. Despite all these advances, therapeutic interventions are still limited. In this article the authors discuss several molecular pathways involved in hypoxia-ischemia, and potential therapeutic targets.
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