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. 2009 Oct;30(5):367-75.
doi: 10.1097/dbp.0b013e3181ba0fcf.

How early do parent concerns predict later autism diagnosis?

Sally Ozonoff  1 , Gregory S Young, Mary Beth Steinfeld, Monique M Hill, Ian Cook, Ted Hutman, Suzanne Macari, Sally J Rogers, Marian Sigman
Affiliations

How early do parent concerns predict later autism diagnosis?

Sally Ozonoff et al. J Dev Behav Pediatr. 2009 Oct.

Abstract

Objective: To study the relationship between parent concerns about development in the first year and a half of life and later autism diagnostic outcomes.

Method: Parent concerns about development were collected for infants at high and low risk for autism, using a prospective, longitudinal design. Parents were asked about developmental concerns at study intake and when their infant was 6, 12, and 18 months. Infants were then followed up until 36 months, when diagnostic status was determined.

Results: By the time their child was 12 months, parents who have an older child with autism reported significantly more concerns in autism spectrum disorders-related areas than parents of children with typical outcomes. These concerns were significantly related to independent measures of developmental status and autism symptoms and helped predict which infants would later be diagnosed with autism or autism spectrum disorders. At 6 months, however, the concerns of parents who have an older child with autism do not predict outcome well.

Conclusion: Explicitly probing for parent concerns about development is useful for identifying children in need of closer monitoring and surveillance, as recommended by the American Academy of Pediatrics.

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Figures

Figure 1
Figure 1
Growth trajectories for ASD concerns. ASD, autism spectrum disorders.
Figure 2
Figure 2
ROC curves at each age for number of ASD concerns (autism/ASD vs. other delays outcome groups). ASD, autism spectrum disorders.
See this image and copyright information in PMC

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