Peripartum cardiomyopathy
- PMID: 18467806
- DOI: 10.3810/pgm.2008.04.1757
Peripartum cardiomyopathy
Abstract
Peripartum cardiomyopathy (PPCM) is a rare, idiopathic, life-threatening disease of late pregnancy and early puerperium, occurring in patients with previously healthy hearts. Risk factors include multiparity, age>30 years, African American race, multiple pregnancies, obesity, hypertension, and toxemia. Signs and symptoms of PPCM resemble systolic heart failure, and it is diagnosed by exclusion. An echocardiogram typically reveals an ejection fraction of <45% and/or fractional shortening of <30%, along with a left ventricular end-diastolic dimension>2.7 cm/m2 of body surface area. Early diagnosis and treatment are important for a successful outcome. Management is similar to other forms of systolic heart failure. Patients with PPCM are at high risk of thromboembolism, and therefore anticoagulation therapy should be considered. The prognosis is variable, ranging from complete recovery, to worsening heart failure requiring cardiac transplantation, or death. Future pregnancies are often discouraged because of the high mortality rate and risk of recurrence.
Similar articles
-
Peripartum cardiomyopathy: a short review.J Indian Med Assoc. 2010 Nov;108(11):764-8. J Indian Med Assoc. 2010. PMID: 21510576 Review.
-
Peripartum cardiomyopathy: current understanding, comprehensive management review and new developments.Postgrad Med J. 2011 Jan;87(1023):34-9. doi: 10.1136/pgmj.2009.096594. Epub 2010 Oct 10. Postgrad Med J. 2011. PMID: 20935342 Review.
-
[Peripartum dilated cardiomyopathy].Tunis Med. 2007 Jun;85(6):473-8. Tunis Med. 2007. PMID: 17644900 French.
-
Peripartum cardiomyopathy: a comprehensive review.Int J Cardiol. 2007 Jun 12;118(3):295-303. doi: 10.1016/j.ijcard.2006.08.005. Epub 2007 Jan 17. Int J Cardiol. 2007. PMID: 17208320 Review.
-
[Peripartum cardiomyopathy-the (un)known obstetricalcardiologic emergency situation].Z Kardiol. 2003 Oct;92(10):811-6. doi: 10.1007/s00392-003-0981-9. Z Kardiol. 2003. PMID: 14579044 Review. German.
Cited by
-
Mitochondrial Function and Dysfunction in Dilated Cardiomyopathy.Front Cell Dev Biol. 2021 Jan 12;8:624216. doi: 10.3389/fcell.2020.624216. eCollection 2020. Front Cell Dev Biol. 2021. PMID: 33511136 Free PMC article. Review.
-
Pregnancy-Associated Heart Failure: A Comparison of Clinical Presentation and Outcome between Hypertensive Heart Failure of Pregnancy and Idiopathic Peripartum Cardiomyopathy.PLoS One. 2015 Aug 7;10(8):e0133466. doi: 10.1371/journal.pone.0133466. eCollection 2015. PLoS One. 2015. PMID: 26252951 Free PMC article.
-
Post-delivery cardiomyopathy in a patient admitted to critical care unit; a rare case report.J Reprod Infertil. 2011 Jan;12(1):37-41. J Reprod Infertil. 2011. PMID: 23926498 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical