Clinical Trial
doi: 10.1007/1-4020-3535-7_15.
Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial
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- PMID: 16137113
- DOI: 10.1007/1-4020-3535-7_15
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Clinical Trial
Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial
Adv Exp Med Biol.
2005.
Abstract
In this placebo controlled, randomised, double blind trial, pregnant women received from the 20th week of gestation onwards either 500 mg docosahexaenoic acid (DHA), 400 mg 5-methyl-tetra-hydro-folate (5-MTHF), or placebo, or a combination of 500 mg DHA and 400 mg 5-MTHF. The dietary supplements were well tolerated; the dropout rates did not differ significantly in the active arms of the study (10% to 19%) from that seen in the placebo group (13%). DHA supplementation resulted in significant enhancement of the contribution of DHA to maternal, placental and venous cord blood lipids.
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