Latest advances in understanding preeclampsia
- PMID: 15947178
- DOI: 10.1126/science.1111726
Latest advances in understanding preeclampsia
Abstract
Preeclampsia is a relatively common pregnancy disorder that originates in the placenta and causes variable maternal and fetal problems. In the worst cases, it may threaten the survival of both mother and baby. We summarize recent work on the causes of preeclampsia, which reveals a new mode of maternal immune recognition of the fetus, relevant to the condition. The circulating factors derived from the placenta, which contributes to the clinical syndrome, are now better understood. This brief review on preeclampsia does not cover all aspects of this intriguing condition but focuses on some new and interesting findings.
Similar articles
-
Preeclampsia: current understanding of the molecular basis of vascular dysfunction.Expert Rev Mol Med. 2006 Jan 26;8(3):1-20. doi: 10.1017/S1462399406010465. Expert Rev Mol Med. 2006. PMID: 16438753 Review.
-
Immunology of pre-eclampsia.Am J Reprod Immunol. 2010 Jun;63(6):534-43. doi: 10.1111/j.1600-0897.2010.00831.x. Epub 2010 Mar 23. Am J Reprod Immunol. 2010. PMID: 20331588 Review.
-
Examination of distinct fetal and maternal molecular pathways suggests a mechanism for the development of preeclampsia.J Reprod Immunol. 2007 Dec;76(1-2):54-60. doi: 10.1016/j.jri.2007.03.012. Epub 2007 May 7. J Reprod Immunol. 2007. PMID: 17482678 Review.
-
The pathogenesis of pre-eclampsia: new aspects.J Perinat Med. 2000;28(6):464-71. doi: 10.1515/JPM.2000.063. J Perinat Med. 2000. PMID: 11155433 Review.
-
Pre-eclampsia: fitting together the placental, immune and cardiovascular pieces.J Pathol. 2010 Aug;221(4):363-78. doi: 10.1002/path.2719. J Pathol. 2010. PMID: 20593492 Review.
Cited by
-
High amniotic fluid fractalkine and MIP-1β levels are associated with intrauterine growth restriction: a prospective cohort study.Turk J Med Sci. 2023 Dec 16;54(1):280-290. doi: 10.55730/1300-0144.5789. eCollection 2024. Turk J Med Sci. 2023. PMID: 38812616 Free PMC article.
-
Immunometric and functional measurement of endogenous vasoinhibin in human sera.Front Endocrinol (Lausanne). 2024 Apr 29;15:1345996. doi: 10.3389/fendo.2024.1345996. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38742198 Free PMC article.
-
Genetic and inflammatory factors underlying gestational diabetes mellitus: a review.Front Endocrinol (Lausanne). 2024 Apr 17;15:1399694. doi: 10.3389/fendo.2024.1399694. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38694942 Free PMC article. Review.
-
The Role of Helicobacter pylori and Metabolic Syndrome-Related Mast Cell Activation Pathologies and Their Potential Impact on Pregnancy and Neonatal Outcomes.J Clin Med. 2024 Apr 18;13(8):2360. doi: 10.3390/jcm13082360. J Clin Med. 2024. PMID: 38673633 Free PMC article. Review.
-
Tadalafil for Treatment of Fetal Growth Restriction: A Review of Experimental and Clinical Studies.Biomedicines. 2024 Apr 4;12(4):804. doi: 10.3390/biomedicines12040804. Biomedicines. 2024. PMID: 38672159 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical