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. 2004 Dec;112(6):548-51.
doi: 10.1111/j.1600-0722.2004.00169.x.

Immunoexpression of extracellular matrix proteins in human salivary gland development

Cristiane Furuse  1 , Patrícia Ramos Cury, Ney Soares de Araújo, Vera Cavalcanti de Araújo
Affiliations

Immunoexpression of extracellular matrix proteins in human salivary gland development

Cristiane Furuse et al. Eur J Oral Sci. 2004 Dec.

Abstract

Immunoexpression of the extracellular matrix (ECM) proteins laminin, fibronectin, tenascin and types I, III and IV collagen was analyzed in the major and minor salivary glands of seven human fetuses at different gestational ages. The results showed the presence and localization of laminin, collagen IV and fibronectin around glandular structures at all stages of development. Tenascin was only detectable around excretory ducts. In the earliest stages of development, type I and type III collagen were presented as fine fibers delineating the glandular structures and delimiting the extension of the future lobule. As glandular development proceeded, the lobule was gradually filled with collagens and glandular tissue.

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