Subsite-specific colorectal cancer incidence rates and stage distributions among Asians and Pacific Islanders in the United States, 1995 to 1999
- PMID: 15247133
Subsite-specific colorectal cancer incidence rates and stage distributions among Asians and Pacific Islanders in the United States, 1995 to 1999
Abstract
Objective: This study examined subsite-specific colorectal cancer incidence rates and stage distributions for Asians and Pacific Islanders (API) and compared the API data with data for Whites and African Americans.
Methods: Data included 336,798 invasive colorectal cancer incident cases for 1995 to 1999 from 23 population-based central cancer registries, representing about two thirds of API population in the United States. Age-adjusted rates, using the 2000 U.S. standard population, and age-specific rates and stage distributions were computed by anatomic subsite, race, and gender. All rates were expressed per 100,000. SEs and rate ratios were calculated for rate comparison. A significance level of 0.05 was used for all analyses.
Results: Overall, age-adjusted colorectal cancer incidence rates were significantly lower in API than in Whites and African Americans across anatomic subsites, particularly for proximal colon cancer in which rates were 40% to 50% lower in API males and females. Exception to this pattern was the significantly (10%) higher rectal cancer incidence rate in API males than in African American males. The incidence patterns by anatomic subsite within API differed from those of Whites and African Americans. Among API, the rate of rectal cancer (19.2 per 100,000) was significantly higher than the rates of proximal (15.2 per 100,000) and distal (17.7 per 100,000) colon cancers in males, with little variations in rates across anatomic subsites in females. In contrast, among White and African American males and females, proximal colon cancer rates were over 25% higher than the rates of distal colon and rectal cancers. Increases in age-specific rates with advancing age were more striking for proximal colon cancer than for distal colon and rectal cancers in Whites and African Americans, while age-specific rates were very similar for different subsites in API with parallel increases with advancing age, especially in API males. Similar to Whites and African Americans, in API, proximal colon cancers (32% to 35%) were also less likely to be diagnosed with localized stage compared with distal colon (38% to 42%) and rectal (44% to 52%) cancers.
Conclusion: The patterns of subsite-specific colorectal cancer incidence in API, especially API males, differ from those of Whites and African Americans. Similar to Whites and African Americans, lower percentage of localized disease in API for proximal colon cancer than for distal colon and rectal cancers was also observed.
Similar articles
-
Colorectal Cancer in Young African Americans: Is It Time to Revisit Guidelines and Prevention?Dig Dis Sci. 2016 Oct;61(10):3026-3030. doi: 10.1007/s10620-016-4207-1. Epub 2016 Jun 9. Dig Dis Sci. 2016. PMID: 27278956 Free PMC article.
-
Racial/ethnic variation in the anatomic subsite location of in situ and invasive cancers of the colon.J Natl Med Assoc. 2007 Jul;99(7):733-48. J Natl Med Assoc. 2007. PMID: 17668639 Free PMC article.
-
Cancer incidence and mortality patterns among specific Asian and Pacific Islander populations in the U.S.Cancer Causes Control. 2008 Apr;19(3):227-56. doi: 10.1007/s10552-007-9088-3. Epub 2007 Nov 27. Cancer Causes Control. 2008. PMID: 18066673 Free PMC article.
-
Colorectal carcinoma in black and white race.Cancer Metastasis Rev. 2003 Mar;22(1):67-82. doi: 10.1023/a:1022264002228. Cancer Metastasis Rev. 2003. PMID: 12716038 Review.
-
Colorectal cancer and race: understanding the differences in outcomes between African Americans and whites.Med Clin North Am. 2005 Jul;89(4):771-93. doi: 10.1016/j.mcna.2005.03.001. Med Clin North Am. 2005. PMID: 15925649 Review.
Cited by
-
The rise of proximal colorectal cancer: a trend analysis of subsite specific primary colorectal cancer in the SEER database.Ann Gastroenterol. 2021 Jul-Aug;34(4):559-567. doi: 10.20524/aog.2021.0608. Epub 2021 Feb 21. Ann Gastroenterol. 2021. PMID: 34276196 Free PMC article.
-
Site-specific risk of colorectal neoplasms in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis.PLoS One. 2021 Jan 25;16(1):e0245921. doi: 10.1371/journal.pone.0245921. eCollection 2021. PLoS One. 2021. PMID: 33493235 Free PMC article.
-
Microbial Community Profiling Distinguishes Left-Sided and Right-Sided Colon Cancer.Front Cell Infect Microbiol. 2020 Nov 26;10:498502. doi: 10.3389/fcimb.2020.498502. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33324571 Free PMC article.
-
Demographics Predict Stage III/IV Colorectal Cancer in Individuals Under Age 50.J Clin Gastroenterol. 2020 Sep;54(8):714-719. doi: 10.1097/MCG.0000000000001374. J Clin Gastroenterol. 2020. PMID: 32520886 Free PMC article.
-
Geographic variation and factors associated with colorectal cancer incidence in Manitoba.Can J Public Health. 2017 Sep;108(5-6):e558-e564. doi: 10.17269/CJPH.108.6091. Epub 2017 Sep 1. Can J Public Health. 2017. PMID: 31823281 Free PMC article.