Critical period regulation
- PMID: 15217343
- DOI: 10.1146/annurev.neuro.27.070203.144327
Critical period regulation
Abstract
Neuronal circuits are shaped by experience during critical periods of early postnatal life. The ability to control the timing, duration, and closure of these heightened levels of brain plasticity has recently become experimentally accessible, especially in the developing visual system. This review summarizes our current understanding of known critical periods across several systems and species. It delineates a number of emerging principles: functional competition between inputs, role for electrical activity, structural consolidation, regulation by experience (not simply age), special role for inhibition in the CNS, potent influence of attention and motivation, unique timing and duration, as well as use of distinct molecular mechanisms across brain regions and the potential for reactivation in adulthood. A deeper understanding of critical periods will open new avenues to "nurture the brain"-from international efforts to link brain science and education to improving recovery from injury and devising new strategies for therapy and lifelong learning.
Similar articles
-
Critical period plasticity in local cortical circuits.Nat Rev Neurosci. 2005 Nov;6(11):877-88. doi: 10.1038/nrn1787. Nat Rev Neurosci. 2005. PMID: 16261181 Review.
-
Critical period mechanisms in developing visual cortex.Curr Top Dev Biol. 2005;69:215-37. doi: 10.1016/S0070-2153(05)69008-4. Curr Top Dev Biol. 2005. PMID: 16243601 Review.
-
Cross-modal plasticity: where and how?Nat Rev Neurosci. 2002 Jun;3(6):443-52. doi: 10.1038/nrn848. Nat Rev Neurosci. 2002. PMID: 12042879 Review.
-
You're perfect, now change--redefining the role of developmental plasticity.Neuron. 2005 Mar 24;45(6):825-8. doi: 10.1016/j.neuron.2005.03.008. Neuron. 2005. PMID: 15797544 Review.
-
A brain adaptation view of plasticity: is synaptic plasticity an overly limited concept?Prog Brain Res. 2002;138:91-108. doi: 10.1016/S0079-6123(02)38073-7. Prog Brain Res. 2002. PMID: 12432765 Review.
Cited by
-
Normative volumes and relaxation times at 3T during brain development.Sci Data. 2024 Apr 25;11(1):429. doi: 10.1038/s41597-024-03267-3. Sci Data. 2024. PMID: 38664431 Free PMC article.
-
Developmental patterns of extracellular matrix molecules in the embryonic and postnatal mouse hindbrain.Front Neuroanat. 2024 Mar 1;18:1369103. doi: 10.3389/fnana.2024.1369103. eCollection 2024. Front Neuroanat. 2024. PMID: 38496826 Free PMC article.
-
Olfactory Critical Periods: How Odor Exposure Shapes the Developing Brain in Mice and Flies.Biology (Basel). 2024 Feb 2;13(2):94. doi: 10.3390/biology13020094. Biology (Basel). 2024. PMID: 38392312 Free PMC article. Review.
-
A critical period for developing face recognition.Patterns (N Y). 2023 Dec 26;5(2):100895. doi: 10.1016/j.patter.2023.100895. eCollection 2024 Feb 9. Patterns (N Y). 2023. PMID: 38370121 Free PMC article.
-
Synaptic plasticity in human thalamocortical assembloids.bioRxiv [Preprint]. 2024 Mar 12:2024.02.01.578421. doi: 10.1101/2024.02.01.578421. bioRxiv. 2024. PMID: 38352415 Free PMC article. Preprint.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources