Improving estimation of cardiac vagal tone during spontaneous breathing using a paced breathing calibration
- PMID: 15133978
Improving estimation of cardiac vagal tone during spontaneous breathing using a paced breathing calibration
Abstract
Respiratory sinus arrhythmia (RSA) is a commonly employed non-invasive measure of cardiac vagal control. It has been demonstrated that respiratory parameters such as tidal volume and respiratory frequency can change RSA without altering tonic vagal activity. Thus, within-individual comparisons of cardiac vagal control across different behavioral tasks might benefit from an adjustment for respiratory confounds. We tested an adjustment method using transfer function analysis and paced breathing at 3 different respiratory frequencies as the basis for regressing out respiratory related RSA changes in a task where breathing was not controlled. Electrocardiogram and calibrated respiration were recorded with the LifeShirt system from 15 young adult participants. Time series of RR intervals and lung volume change were computed and the respiration-to-RR-interval transfer-function magnitude (RSA-TF, in ms/liter) estimated. Mean (SD) of RSA-TF was 142 (68) at 9 breaths/min, 78 (52) at 13.5 breaths/min, 57 (43) at 18 breaths/min, and 121 (56) during baseline, with a respiratory frequency of 12.5 (3.8) breaths/min. At baseline, measured and predicted RSA-TF values (mean 94 +/- 82) differed significantly and correlated only moderately (r = 0.67). Factors contributing to a less than perfect correlation included slightly elevated subjective anxiety levels and hyperventilation during paced breathing, both of which may have affected cardiac vagal tone. This study demonstrates a novel procedure for computing a respiratory unrelated RSA index. Results provide some support for the utility of this adjustment method for improving the estimation of cardiac vagal tone from RSA, but also indicate that the paced breathing procedure may need to be further refined.
Similar articles
-
[Research progress of quantitative analysis for respiratory sinus arrhythmia].Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2011 Dec;28(6):1227-31. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2011. PMID: 22295719 Review. Chinese.
-
A MATLAB toolbox for correcting within-individual effects of respiration rate and tidal volume on respiratory sinus arrhythmia during variable breathing.Behav Res Methods. 2009 Nov;41(4):1121-6. doi: 10.3758/BRM.41.4.1121. Behav Res Methods. 2009. PMID: 19897819
-
Studying noninvasive indices of vagal control: the need for respiratory control and the problem of target specificity.Biol Psychol. 2009 Feb;80(2):158-68. doi: 10.1016/j.biopsycho.2008.08.003. Epub 2008 Aug 15. Biol Psychol. 2009. PMID: 18775468
-
Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functions.Biol Psychol. 2007 Feb;74(2):263-85. doi: 10.1016/j.biopsycho.2005.11.014. Epub 2006 Nov 1. Biol Psychol. 2007. PMID: 17081672 Review.
-
Enhanced cardiac vagal efferent activity does not explain training-induced bradycardia.Auton Neurosci. 2004 May 31;112(1-2):60-8. doi: 10.1016/j.autneu.2004.04.006. Auton Neurosci. 2004. PMID: 15233931
Cited by
-
Risk for internalizing symptom development in young children: Roles of child parasympathetic reactivity and maternal depression and anxiety exposure in early life.Psychophysiology. 2023 Oct;60(10):e14326. doi: 10.1111/psyp.14326. Epub 2023 May 10. Psychophysiology. 2023. PMID: 37162341
-
Third Trimester Fetuses Demonstrate Priming, a Form of Implicit Memory, In Utero.Children (Basel). 2022 Oct 31;9(11):1670. doi: 10.3390/children9111670. Children (Basel). 2022. PMID: 36360397 Free PMC article.
-
The Effects of Mindfulness and Meditation on Vagally Mediated Heart Rate Variability: A Meta-Analysis.Psychosom Med. 2021 Jul-Aug 01;83(6):631-640. doi: 10.1097/PSY.0000000000000900. Psychosom Med. 2021. PMID: 33395216 Free PMC article.
-
Cardiac sympathetic activation and parasympathetic withdrawal during psychosocial stress exposure in 6-month-old infants.Psychophysiology. 2020 Dec;57(12):e13673. doi: 10.1111/psyp.13673. Epub 2020 Oct 13. Psychophysiology. 2020. PMID: 33048371 Free PMC article.
-
Central autonomic network functional connectivity: correlation with baroreflex function and cardiovascular variability in older adults.Brain Struct Funct. 2020 Jun;225(5):1575-1585. doi: 10.1007/s00429-020-02075-w. Epub 2020 Apr 30. Brain Struct Funct. 2020. PMID: 32350644 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Miscellaneous