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Review
. 2004 Jan 31;363(9406):381-91.
doi: 10.1016/S0140-6736(04)15440-8.

Migraine

Affiliations
Review

Migraine

Stephen D Silberstein. Lancet. .

Abstract

Migraine is a very common neurobiological headache disorder that is caused by increased excitability of the CNS. It ranks among the world's most disabling medical illnesses. Diagnosis is based on the headache's characteristics and associated symptoms. The economic and societal effect of migraine is substantial: it affects patients' quality of life and impairs work, social activities, and family life. There are many acute and preventive migraine treatments. Acute treatment is either specific (triptans and ergots) or non-specific (analgesics). Disabling migraine should be treated with triptans. Increased headache frequency is an indication for preventive treatment. Preventive treatment decreases migraine frequency and improves quality of life. More treatments are being developed, which provides hope to the many patients whose migraines remain uncontrolled.

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Comment in

  • Migraine.
    Lee AH. Lee AH. Lancet. 2004 Apr 24;363(9418):1398; author reply 1399. doi: 10.1016/S0140-6736(04)16062-5. Lancet. 2004. PMID: 15110506 No abstract available.
  • Migraine.
    Soothill JF. Soothill JF. Lancet. 2004 Apr 24;363(9418):1398-9; author reply 1399. doi: 10.1016/S0140-6736(04)16063-7. Lancet. 2004. PMID: 15110507 No abstract available.

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