Depression and pain comorbidity: a literature review
- PMID: 14609780
- DOI: 10.1001/archinte.163.20.2433
Depression and pain comorbidity: a literature review
Abstract
Because depression and painful symptoms commonly occur together, we conducted a literature review to determine the prevalence of both conditions and the effects of comorbidity on diagnosis, clinical outcomes, and treatment. The prevalences of pain in depressed cohorts and depression in pain cohorts are higher than when these conditions are individually examined. The presence of pain negatively affects the recognition and treatment of depression. When pain is moderate to severe, impairs function, and/or is refractory to treatment, it is associated with more depressive symptoms and worse depression outcomes (eg, lower quality of life, decreased work function, and increased health care utilization). Similarly, depression in patients with pain is associated with more pain complaints and greater impairment. Depression and pain share biological pathways and neurotransmitters, which has implications for the treatment of both concurrently. A model that incorporates assessment and treatment of depression and pain simultaneously is necessary for improved outcomes.
Comment in
-
Depression and pain: the road to evidence-based care.Arch Intern Med. 2003 Nov 10;163(20):2415-6. doi: 10.1001/archinte.163.20.2415. Arch Intern Med. 2003. PMID: 14609773 No abstract available.
-
Sex hormone deficiency in depressed patients receiving opioids.Arch Intern Med. 2004 Apr 12;164(7):804; author reply 805. doi: 10.1001/archinte.164.7.804-a. Arch Intern Med. 2004. PMID: 15078652 No abstract available.
-
An obstacle to the treatment of depression.Arch Intern Med. 2004 Apr 12;164(7):804; author reply 805. doi: 10.1001/archinte.164.7.804-b. Arch Intern Med. 2004. PMID: 15078653 No abstract available.
-
Discussing the depression-pain dyad with patients.Arch Intern Med. 2004 Apr 12;164(7):804-5; author reply 805. doi: 10.1001/archinte.164.7.804-c. Arch Intern Med. 2004. PMID: 15078654 No abstract available.
Similar articles
-
Pain and depression: the egg and the chicken story revisited.Arch Gerontol Geriatr. 2009;49 Suppl 1:103-12. doi: 10.1016/j.archger.2009.09.018. Arch Gerontol Geriatr. 2009. PMID: 19836622 Review.
-
Antidepressant agents for the treatment of chronic pain and depression.Pharmacotherapy. 2007 Nov;27(11):1571-87. doi: 10.1592/phco.27.11.1571. Pharmacotherapy. 2007. PMID: 17963465 Review.
-
Predictors of pain outcomes in patients with chronic musculoskeletal pain co-morbid with depression: results from a randomized controlled trial.Pain Med. 2010 Apr;11(4):482-91. doi: 10.1111/j.1526-4637.2009.00759.x. Epub 2009 Dec 9. Pain Med. 2010. PMID: 20002592 Clinical Trial.
-
Posttraumatic stress disorder and physical comorbidity among female children and adolescents: results from service-use data.Pediatrics. 2005 Dec;116(6):e767-76. doi: 10.1542/peds.2005-0608. Pediatrics. 2005. PMID: 16322133
-
Depression and chronic medical illness.J Clin Psychiatry. 1990 Jun;51 Suppl:3-11; discussion 12-4. J Clin Psychiatry. 1990. PMID: 2189874 Review.
Cited by
-
Pain and psychopathology after intensive care unit admission.Anaesth Intensive Care. 2024 Jul;52(4):232-240. doi: 10.1177/0310057X241226716. Epub 2024 Jun 16. Anaesth Intensive Care. 2024. PMID: 38879797 Free PMC article.
-
Effect of intramuscular diazepam infusion on herpes zoster-related pain in older patients: a randomized, double-blind, placebo-controlled trial.BMC Anesthesiol. 2024 May 29;24(1):193. doi: 10.1186/s12871-024-02576-9. BMC Anesthesiol. 2024. PMID: 38811866 Free PMC article. Clinical Trial.
-
Pain Catastrophizing: How Far Have We Come.Neurol Int. 2024 Apr 26;16(3):483-501. doi: 10.3390/neurolint16030036. Neurol Int. 2024. PMID: 38804476 Free PMC article. Review.
-
Enhancing Chronic Non-Cancer Pain Management: A Systematic Review of Mindfulness Therapies and Guided Imagery Interventions.Medicina (Kaunas). 2024 Apr 23;60(5):686. doi: 10.3390/medicina60050686. Medicina (Kaunas). 2024. PMID: 38792869 Free PMC article. Review.
-
The Association of Central Sensitisation with Depression, Anxiety, and Somatic Symptoms: A Cross-Sectional Study of a Mental Health Outpatient Clinic in Japan.Life (Basel). 2024 May 10;14(5):612. doi: 10.3390/life14050612. Life (Basel). 2024. PMID: 38792633 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical