Oxidized LDL and atherogenesis
- PMID: 10415527
- DOI: 10.1111/j.1749-6632.1999.tb09231.x
Oxidized LDL and atherogenesis
Abstract
A brief review of recent findings regarding the role of oxidized low-density lipoproteins (Ox-LDL) in atherogenesis. Lipid peroxidation and oxidative damage to LDL make arteries susceptible to chronic inflammation, which is known to cause alterations in arterial gene expression and promote lesion development. Treatment protocols implementing antioxidants for preventing cardiovascular diseases are suggested.
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